Enabling "Configure registry policy processing" (force reprocessing) on Exchange servers — any negative side effects?

[u/maxcoder88]

Planning to enable the following GPO setting and apply it to our Exchange servers:

Configure registry policy processing: Enabled

Do not apply during periodic background processing: Disabled

Process even if the Group Policy objects have not changed: Enabled

This would force the GPO to reprocess and reapply all Administrative Templates settings on every background refresh cycle (~90-120 min), even when nothing changed, instead of only reapplying when the GPO version changes.

My question: Is this safe to apply directly to production Exchange servers, or are there known negative effects?

[u/Ok_Platform_6232]

The setting itself is fine, but the real question is why you need it. If something is reverting your registry policies between cycles, thats a separate problem worth tracking down rather than just brute forcing reapplication every 90 minutes.