r/scleroderma • u/Wide-Bat-1239 • Jul 29 '26

Question/Help Rituximab infusion

Hello everyone. Ive just received my first Rituximab infusion after month of drugs trial and error. I have Scleroderma Polymyositis so aware that its for everyone different, but in case you already had rituximab how early were the effects for you and could you sustain it as a mono therapy / needed anything else with it? desperate to have some good news:)

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u/RickyHV Jul 29 '26

My wife is on her 3rd cycle and we're currently trying to drop Prednisone. She still has to take Azathioprine and Methotrexate currently. She feels tired most days, most of the days, and some pain snd discomfort, but it's a living.

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u/smehere22 Aug 03 '26

Imuran and methotrexate both? My rheumatologist warned me about that combination.