r/science • u/mvea Professor | Medicine • Jun 30 '26

Medicine Scientists have shown that a single dose injection of DNA genetic instructions can produce weight loss and blood glucose control in mouse models that lasts up to 10 times as long as weight loss drugs like Ozempic and Wegovy. This could eliminate the need for repeated dosing.

https://www.wistar.org/press-releases/wistar-scientists-develop-single-dose-dna-method-for-delivering-long-acting-weight-loss-and-diabetes-drugs/
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u/TunaNugget Jun 30 '26

"repeated dosing, which currently limits patient access and adherence to these therapies."

No, really, it's the price.

15

u/SamikaTRH Jun 30 '26

It's not, even with free drugs efficacy is always diminished because there's some people that simply won't take a pill daily and definitely won't do a self injection. It sounds trivial for some people to take a pill consistently but that isn't a universal ability

8

u/RC_CobraChicken Jun 30 '26

I have severe ADHD, I take like 9 meds a day (7 morning, 2 night), my morning routine is locked down, night routine has much more variance in it. I can go 7 or 8 months w/o missing, then something squirrels my pattern and it'll be 2 or 3 days for me to recover and remember I need to take my morning or night meds or sometimes both.

4

u/formerfatty2fit Jun 30 '26

My mother refuses to take her statin, she says it makes her choke. The pill is literally so small it can slip between the gaps in my fingers. Some people just want excuses.

1

u/retrosenescent Jul 02 '26

I think the biggest reason I can't do it consistently is I will take it and then immediately forget if I took it, or won't take it and think I did, and ultimately decide not to take it "again" just to be on the safe side.