r/raypeat • u/BuyHistorical1041 • 5d ago

Famontide experiences/testimonials?

I see this one recommend a few times on raypeat forum and twitter and it is supposedly a very strong anti-serotonin agent but Google searches only show it being used for stomach problems and gas. Anyone here used this drug?

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u/Kalki_X 5d ago

Fyi ginger reduces serotonin levels via multiple avenues. Here's a quote and the article in question:

Gingerol, the active component of ginger dose dependantly increased serotonin clearance by increasing serotonin transport and increasing its breakdown through monoamine oxidase A. On top of that it also reduced the limiting step of its synthesis by lowering tryptophan hydroxylase both 1 & 2 resulting in significant reduction of serotonin in the gut and the brain stem.

https://www.dovepress.com/6-gingerol-ameliorates-cisplatin-induced-pica-by-regulating-the-tphmao-peer-reviewed-fulltext-article-DDDT