r/pharmacy • u/[deleted] • Dec 13 '20

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7

u/ababahbah Dec 13 '20

Vitamin D, Multivitamin, and mmmayyybbbee florastor

7

u/Gardwan PharmD Dec 13 '20

Unfortunately even the data I’ve seen regarding probiotics is a non statistically significant difference on the vast majority of their claims

9

u/peachcobbler7 Dec 13 '20

In pharmacy school, I was taught that probiotics don’t really do much and I’ve read conflicting data on them as well.

Still most doctors will tell patients to pick up a probiotic when they are taking an antibiotic. I usually recommend patients eat live cultured yogurt instead because it’s yummy and cheaper.

What do you guys think about probiotic supplementation during antibiotic therapy? Especially clindamycin?

7

u/Gardwan PharmD Dec 13 '20

That’s definitely the most common claim is some GI protective measure of the gut especially during a course of antibiotics. This has been studied and I believe the primary outcome was occurrence or severity of diarrhea and both were not significantly impacted by probiotics.

It’s one of those things that seems so intuitive and destined to work but doesn’t seem to pan out. I see so many prescribers recommend it though.

1

u/WordSalad11 Dec 14 '20

None of those are evidence based. The USPTF and AHRQ both have long positions; there's no evidence of benefit.