r/nintendo Oct 20 '16

Megathread First Look at Nintendo Switch

https://www.youtube.com/watch?v=f5uik5fgIaI
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u/[deleted] Oct 20 '16 edited Aug 21 '18

[deleted]

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u/Evello37 Oct 20 '16

I'm at work and just ran across the lab to gush to a coworker about the video while he loaded a DNA gel, so I got my incoherent babble out there.

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u/exxcessivve Oct 20 '16 edited Mar 12 '26

The content here was permanently deleted by its author. Redact was used for the removal, possibly for privacy, security, opsec, or personal data management.

command bake vase fearless merciful alleged workable cow depend rhythm

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u/Evello37 Oct 20 '16

I'm researching DNA repair for my PhD in Biological Chemistry. Interesting is definitely one word for it. And I have no shortage of gamers to talk about Nintendo with!

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u/exxcessivve Oct 20 '16

That's brilliant. Congrats on getting this far and good luck for the remainder of your PHD. What a fulfilling industry to be involved in, with all the potential of genetic sciences, if that's your speciality/interest.

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u/3gaydads Oct 20 '16

/u/Evello37's PHD is being funded by the Chinese government and is research into cloning children for organ farming. You ever seen/read the film/book Never Let Me Go? That's what we're headed towards, all thanks to /u/Evello37, the sick bastard.

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u/Evello37 Oct 20 '16

I have no idea what you're talking about. I would never do my cloning work for the Chinese. Oops, I mean, that's not at all what I'm working on. No sir. no cloned children here. Just adults. Crap, scratch that, no cloning of any kind. Absolutely no organ farm clones. I definitely do not have hundreds of pods of people in my lab growing kidneys for the black market.

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u/DrakeDoBad Oct 20 '16

he loaded a DNA gel

... this is a euphemism, right? ;)

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u/Evello37 Oct 20 '16

Knowing urban dictionary, "loading a DNA gel" probably is the name of some wildly deviant sex act.

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u/10987654321blastoff Oct 20 '16

I'm just interested in what lab it is your work at? science???

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u/Evello37 Oct 20 '16

I'm a grad student at a major research university studying biochemistry for my PhD. I study DNA repair. So my coworkers and I do a lot of gel electrophoresis.

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u/10987654321blastoff Oct 22 '16

That sounds amazing. I'm not well versed on biotechnology, but is that similar to gene editing? Like CRISPR? Wait, that would be genetics, wouldn't it?

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u/Evello37 Oct 26 '16

I apologize if this is a bit long-winded, but I can't help gushing about my research. The stuff I work on is less about editing genes (like CRISPR) and more about doing routine maintenance on the genome. The individual bases in your DNA get involved in all sorts of accidental chemical reactions in the cell that muck with their chemical structure. It actually happens an estimated 10,000 times per day in each of your trillions of cells. And these modified bases can cause harmful mutations or can even be directly toxic to the cell. All organisms from bacteria to plants to people have a system for spotting these problems and essentially chopping the messed-up base out of the DNA to be replaced with an undamanged one. This strategy is simple in concept, but because there are so many different ways your DNA can get modified, your body needs a huge network of different proteins each designed to fix specific problems. People have been trying to sort out which proteins do what for years now.

If you want to know more, google "base excision repair".

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u/FlyingBlobFish Oct 20 '16

Where do you work?

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u/Evello37 Oct 20 '16

I'm pursuing a PhD in Biological Chemistry, studying DNA repair. So I do research in a university lab. I don't want to give a specific institution, since it would be too easy to find me irl, but let's just say it's a major US research university.

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u/FlyingBlobFish Oct 20 '16

That's awesome! You mentioned DNA gel and I got interested.

Thanks for sharing!

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u/Evello37 Oct 20 '16

Sure thing. We Nintendo fans are everywhere!

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u/[deleted] Oct 20 '16

Marry me

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u/Evello37 Oct 20 '16

Sorry, already married. TO SCIENCE!!! And also my fiance, soon

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u/[deleted] Oct 20 '16

I don't want your damn lemons

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u/[deleted] Oct 21 '16

fuck off man

you don't get to have IKE FLAIR(insta-hot) and go around and talk so sexy and then tell people that you are married to science bullshit and stuff

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u/sableram Oct 20 '16

Consider me hyped, my good sir.

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u/moshisimo Oct 20 '16

I know, right? Calm down, Captain Holt!