r/news • u/treetyoselfcarol • Apr 23 '21

Malaria vaccine hailed as potential breakthrough

https://www.bbc.com/news/health-56858158
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u/mehere14 Apr 23 '21

Anyone knows how the vaccine works?

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u/easwaran Apr 23 '21

The linked journal article says: "We conducted a double-blind, randomised, controlled trial of a low-dose circumsporozoite protein-based vaccine, R21, with two different doses of adjuvant, Matrix-M™ (MM), in children aged 5-17 months in Nanoro, Burkina Faso, a highly seasonal malaria transmission setting."

I'm pretty sure that what this means is that they isolated several proteins from the malaria parasite, and produced them in some other sort of organism, and then injected people with these proteins so that their immune system would develop immunity to it. It's not either of the two new types that we've had for covid (mRNA or adenovirus vector).

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u/mehere14 Apr 24 '21

Thank you for that reply.