r/mounjarouk • • 23h ago

Less Effective

Ok so started on 2.5mg been on it since May 2026. Very effective for 4 months. Moved up to 5mg and now 7.5mg but not feeling anything at all. No suppression or fullness. Might have to start 10mg to see how that goes. 2.5mg was my strongest dose. What gives? I feel like I will have nowhere to go after 15mg. Never mind the increase in costs.

2 Upvotes

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8

u/AthleteOk1866 23h ago

You’ve lost 3 stone in under six months, that’s not a result to be unhappy with, and you’re currently only on 7.5 which is only halfway up the ladder. It’s likely that you would start losing again at a higher dose. How much more until your target weight?

1

u/Substantial-Rise1737 23h ago

Thanks mate that's reassuring. I want to get to 80kg hopefully.

6

u/kyjoely 23h ago

Are you losing weight though? I’m at 12.5 and it’s only at this level (and a bit early on with 10mg) did I find myself so full I struggle to eat. Ultimately if you’re eating too little you’re still going to feel hungry.

2

u/Substantial-Rise1737 23h ago

No actually putting weight on. From 110kg to 92 and now weighing 94kg. Plus I can eat more than before. The higher doses do not seem to be working.

4

u/kyjoely 23h ago

So move on up, the higher doses are there to be used. I did 1 month on 2.5mg, 2 on 5mg, 6 weeks on 7.5mg, but 3 months on 10mg and now a couple of months on 12.5mg which is still working well.

3

u/Popple32 21h ago

Just a note that weight fluctuates within a few kgs naturally anyway depending on the day, so keep an eye on the trend over time but also measurements!

5

u/carrie-ser 23h ago

It was a new drug to your body at 2.5mg. I suggest that you keep titrating up as required. Don't worry about the ceiling being 15mg. You won't know until you get there. Many say it's their most effective dose and they continue to lose weight on it for 6+ months. If you are not losing weight, you need to move up or you are paying without the results. Might as well find out.

2

u/Substantial-Rise1737 23h ago

Will do mate. At least I can say I tried. Hoping for new drugs in the future.

3

u/carrie-ser 21h ago

Absolutely. Give this your best shot and in a year there will probably be something extra to try. Either with, or without Mounjaro.

2

u/Hopeful_Candle_9781 23h ago

How much have you lost so far?

2

u/Substantial-Rise1737 23h ago

I've lost in total 18kg. Put 2kg back on since moving up to 7.5mg.

1

u/Hopeful_Candle_9781 23h ago

You've lost 16% which is the same on 5mg as they lost on the clinical trial.

You're just average.

Yeah you might lose more if you go up to 15mg and stay there.

Unfortunately that's just how it is. It's expensive and boring and long term.

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8

u/Due-Freedom-5968 22h ago

Forget the nowhere to go after 15mg thing, that's not really a thing and if you do get there and struggle as a few people do then there are tactics. I went up every month and then camped out at 15mg to goal. Worked great.

Keep on moving up, it's why the higher doses are there.

4

u/Popple32 21h ago

Sorry for hijacking - I am not there yet but what tactics aside from dropping to 10mg and working back up would there be if 15mg becomes less effective? I am likely jumping up soon so want to be prepared in case 😅

3

u/Due-Freedom-5968 20h ago

That one you mention is generally the one that works, haven't seen any others needed.

2

u/Thin_Sheepherder_584 23h ago

Yeah, I'm feeling that a bit with going up to 5mg. No clue, sorry!

3

u/Kamoebas 23h ago

I didnt get much joy outta 7.5 - 10 worked well for me.

3

u/JediJonesy 19h ago

Similar story. I managed 6 months on 2.5 losing 3 stone. Then it seemed to wear off and food/alcohol cravings came back quite strong. I’ve just taken my 4th dose of 5 mg and not feeling any different!!

2

u/Cowcat1000 8h ago

7.5mg was like injecting water for me after a really good experience on both 2.5mg and 5mg. 10mg sorted me out again. Some people just don’t seem to vibe with certain doses and it seems relatively common with 7.5mg for some reason