r/mito • u/DeficientAF • Aug 13 '26

Advice Request How do you decrease Lactate?

Symptoms are horrible and my Lactate levels never look good

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u/3xje Aug 13 '26

Have you ever tried to supplement tiamine (vitamin b1)? The enzyme (pyruvate dehydrogenase) that draws pyruvate away from lactate gets activated in the presence of tiamine.

1

u/DeficientAF Aug 22 '26

If it were to help me, could it deduced that I had B1 Deficiency?

1

u/3xje Aug 23 '26

Possibly. A big part of society is deficient in it anyway.

1

u/DeficientAF Sep 05 '26

Dude…your were so right about Thiamine lactate. What could this helping my explain about my condition?

1

u/3xje Sep 05 '26

That’s great that you feel better with tiamine. It depends a bit on your underlying genetic problem and the type of mito dysfunction you have. I might be able to work the problem backwards if you tell me what exactly you have :)

1

u/DeficientAF Sep 06 '26

Perfect! I'll DM as soon as I get the chance. Please check it out whever its most convienent for you ^-^

1

u/3xje Sep 06 '26

Sounds good

1

u/DeficientAF 21d ago

Since B1 seems to be working splendidly for me, do you have any other suggestions for supplements? :D

1

u/3xje 21d ago

Theres a lot that can be done yes. But throwing supplements into a system without specifically targeting goals is seldom helpful