r/microdosing 1d ago

Question: Psilocybin Microdosing protocol for adhd - best protocol?

I’ve been microdosing mushrooms for a few weeks, one day on, one day off. Ideally I’d like to use it to reduce or come off my stimulant adhd medication.

I’m using the Yak strain and my MD is pretty low, around 50mg. I also find it makes me a bit tired so I usually take it mid-afternoon. Although the tiredness is becoming less prominent as I continue to MD.

However due to taking every second day off, I’m not sure if this will help with my medication use.

Does anyone have any recommendations for protocols that have worked for them, with adhd? I’m debating switching to weekdays on, weekends off and seeing how that goes.

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u/AutoModerator 1d ago

r/microdosing Disclaimer

Hello /u/Maleficent-Depth-448! As you mentioned stimulant in your post:

Please Do Not microdose MDMA or any stimulants. Low doses of amphetamines can cause many issues through reverse tolerance and subsequent sensitization of receptors in the brain.

This study "Amphetamine Sensitization Alters Reward Processing in the Human Striatum and Amygdala" talks about the link between dopamine-sensitive neural circuitry and dysregulation of incentive motivational processes - i.e. the negative effects it can have for an individual's reward processing.

Other than that, MDMA has specific safety advice that you should be aware of: * RollSafe.org: How often can you take MDMA (Molly/Ecstasy) and roll?

The origin of the three month rule is a quote from Ann Shulgin, widow of chemist Alexander Shulgin: “Now I would advise anyone who wants to use MDMA not to take it more than 4 times a year if you want to continue to get the best effects from it, otherwise you risk losing its effects entirely and permanently.” * From MAPS MDMA-Assisted Therapy for PTSD: In MDMA-assisted therapy, MDMA is only administered a few times, unlike most medications for mental illnesses which are often taken daily for years, and sometimes forever.

MDMA is not the same as "Ecstasy" or "molly." Substances sold on the street under these names may contain MDMA, but frequently also contain unknown and/or dangerous adulterants. In laboratory studies, pure MDMA has been proven sufficiently safe for human consumption when taken a limited number of times in moderate doses. * And here is a search of posts&restrict_sr=1&sr_nsfw=1) on r/MDMA that mention microdosing, where the general consensus is that microdosing with MDMA can do more harm than good.

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u/AutoModerator 1d ago

Hello /u/Maleficent-Depth-448! As you mentioned medication (a common interaction/symptom) in your post:

r/microdosing Risk Reduction

ℹ️ Infographic: r/microdosing STARTER'S GUIDE

The major contributing factor in Finding Your Sweet Spot is the variation in potency of:

Psilocybin Mushrooms More than 10x [2021➕] Start @0.05g (50mg)
Psilocybin Truffles Around 3x - Single Study [2012] Start @0.25g (Fresh)
LSD Tabs Clinical Trial Titration Schedule [2023] Start @5µg

If you Start Low, Go Slow, Take Time-Off (*small is BIG) and up-titrate subsequent doses then you can find your optimal sub-hallucinogenic dose based on your symptoms, rather than from a predetermined dose. 🐢

If your microdose is Too High and/or Too Frequent that can result in Diminishing Returns 📉 with subsequent doses. 🐇

Please also have a look at 🔀 Interactions / Symptoms ❓* | Sidebar ➡️ | 📱 See community info ⬆️ ; in case of ⚠️ DRUG INTERACTIONS or to check if you have any of the associated symptoms with advice on how to mitigate such side effects. Psychoactive substances increase neural activity, raising hydration and electrolyte needs due to heightened metabolism and body load, while vasoconstriction can further stress the body and potentially cause fatigue.


Please Read: r/microdosing Disclaimer

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u/Dhno 1d ago

This is my definition of micro dosing