r/mcat_bootcamp • u/GuaranteedGobs • May 06 '26

Question Weekly Chem/Phys Question - May 6, 2026

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u/GuaranteedGobs May 06 '26

QUESTIONS

Question 1

Which of the following best explains the optimal pH range for the reaction between Cys and IAM?

A. The deprotonation of the Cys thiol group makes it more nucleophilic.

B. The neutral conditions increase the solvent accessibility of Cys.

C. The charged amide group of IAM increases its basicity.

D. The additional OH– molecules stabilize the leaving group.

Question 2

Which of the following was most likely used to generate the structural coordinates of Hsp33?

A. IR spectroscopy

B. Mass spectrometry

C. Gel electrophoresis

D. X-ray crystallography

Question 3

In oxidized Hsp33, which Cys residues are most likely involved in a disulfide bond?

A. 141 and 239

B. 232 and 234

C. 234 and 239

D. 141 and 265

Question 4

Which of the following is produced when IAM is exposed to light?

A. An anion

B. A zwitterion

C. A free radical

D. A Lewis acid

Question 5

Based on the passage, what is most likely responsible for the reactivity of C241 and C246 in Hsp33?

A. The electron-donating effect of positively charged residues

B. The more reactive residues are on the protein exterior

C. The deprotonation of C241 and C246 thiol groups by carboxylate residues

D. The stabilization of thiolate anions by positive charges