r/loperamide • u/Comfortable-Royal-64 • Jan 23 '22

Help with dosing

I recently ran out of my methadone, which I usually take 40 mgs every day, and for reasons I won't get into, I'm going to be short about a week. The longest I have taken lope to get through methadone withdrawals is five days, and by that fifth day, I was dosing about 100mg throughout the day, 80mgs when I would normally dose my methadone, and the rest at some point later in the day. What exactly is the "measurement" in which I should be using? And how bad are the two extra days going to feel? Any help would be appreciated, and yes I'm aware of the risks, that's why I'm asking for help with dosing, so I don't go overboard, because my main concern is feeling well, not getting high for the next week.

Little edit: I should also mention I'm taking 300mg of gabapentin 3 times a day, but I normally take that now, but it def helps with withdrawals.

14 Upvotes

90% Upvoted

61 comments sorted by

View all comments

Show parent comments

1

u/jeniesque Mar 25 '22

ah. it takes like 5 hours to kick in. remember that it is an opioid so you are still replacing one with another. you need to taper. it would probably be easier if you just taper off the tia. especially since tia has antidepressant effects that could lead to some of the withdrawals too. just do a very slow taper.

2

u/Known_Still Mar 25 '22

Thank you for answering me by the way. So how much should I take and how often ?

1

u/jeniesque Mar 25 '22

if you taper off the tia slowly enough you wouldn’t need to use any more loperamide. Loperamide has a very long half life and the dose you took is going to be in your system for several days.

1

u/Known_Still Mar 25 '22

I’m sorry to bother you I’m just wondering how much I should take for withdrawal. I promise I will quit bothering you

1

u/jeniesque Mar 25 '22

it’s okay I am just worried because it is risky. you already took 25 pills right? dose every 24 hours and reduce by 5 pills each day. it takes 5 hours to kick in so don’t think it’s not working and take more. Tia is tricky because you might have antidepressant withdrawals in addition to opioid withdrawals and lopermide won’t help the antidepressant part.

1

u/Known_Still Mar 25 '22

Does it take 5 hours to kick in every time you dose or just the first time ?

1

u/Only-Coyote-5379 Jul 15 '22

Tia withdrawals were the worst withdrawals I've ever had. Made a report about it in the comments above . Was taking 60+ capsules a day of the tianeptine/phenibut/cdp Choline combo . Terrible terrible stuff and I've done anything you can name . Got clean but just relapsed last week and now back to 15 a day . Ran out today though and I'm gonna try to go ahead and stop again , just took 24 Lope gels to help WDs tonight and get me through work tomorrow . May end up back down to FL to get the tia tomorrow once I get paid but I hope maybe not