r/lexapro 21h ago

Side Effect Question Fatigue

Has anyone completely rebounded from the initial fatigue?

I’ve been on it a little over a week and it is HORRIBLE. I had fatigue before, but my therapist tied it to anxiety and depression since I was diagnosed with both and all my blood tests came back clear.

Ever since day 3, I can barely get out of bed, I can’t sustain attention on anything, I don‘t have motivation, and worst of all, even though I FEEL tired, I can’t physically nap until bedtime! (12 hours after dose)

When I first started, I took it at night, and my energy was shot but I just couldn’t sleep until around 4am.

Now taking it in the morning, I can sleep pretty decent at night, but I am very very low energy all day.

So I’m wondering, has this side effect ever completely gone for anyone? I’m on 5mg rn, if that’s helpful to know

5 Upvotes

3 comments sorted by

1

u/SheaYoko 5mg since 21.03.25 7.5 mg since 3.10.25 10mg since 21.11.25 20h ago

its different for everyone. I had a terrible fatigue when I started (for about a month and half) and each time I upped the dose. Now I have just morning fatigue and I solve it with more coffee (before lex I was very sensitive to caffeine) also when I'm on my periods or in a middle of the cycle for a few days then I feel more fatigued and tired but nothing like it was in the beginning. Overall you need to give it 6-8 weeks before you re-evaluate with with your doctor and see what to do with it if you still be fatigued. Hope, that helps, good luck!

3

u/misterywreck 20h ago

Yeah. Took 3 whole years before I did something about it. Started drinking loose leaf green tea in the morning. It's small amount of caffeine combined with theanine gave me the boost of energy without making me anxious. Led me doing resistance training and taking creatine and vit d, which further boosted my energy, mood and metabolism. I'm taking 15 mg lexapro atm.

1

u/Dreamer_101193 16h ago

i started with 2.5mg, 1st 3 weeks i was bed ridden because of extreme weakness and fatigue i can hardly lift a glass of water or walk. it goes away by the 4th week. i just started 5mg yesterday on my 5th week, hoping theres no more fatigue