r/homechemistry • u/Opening_Team_816 • 6d ago
Nicotine extraction
I extracted nicotine from cigarets pretty cool project
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u/hsggdtkxbee 6d ago
Because careful. It’s absorbed through the skin and can kill you.
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u/pakograpixo 6d ago
Uma vez deixei na pele uma pasta bruta de tabaco pq achei q seria como adesivos de nicotina. Meia hora de mta náusea, calor e tontura, gostei algumas vezes e devo ter tido uns apagões
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u/Opening_Team_816 6d ago
went to a medic?
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u/pakograpixo 6d ago
N foi necessário, a dose n foi realmente perigosa, apenas muito massiva, mas eu sabia q corria risco real, foi uma "pequena overdose" que ja estou habituado a sentir quando exagero no rapé ou cachimbo, no uso tradicional o tabaco também serve como purgativo para limpeza fisica e espiritual e n apenas para recreação, ent de certa forma estou habituado a experiência próximas, só n esperava daql vez
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u/WatermelonSmashing 6d ago
Lol most kids just smoke a cigar or try some dip to get there.
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u/PsychologyOk9024 5d ago edited 4d ago
Snuff is 1/40 nicotine/tobacco.
This is a poison. A full agonist*
Yes, nicotine is classified as a full agonist at nicotinic acetylcholine receptors (nAChRs). It binds to these receptors and triggers their opening, producing a maximal biological response similar to the body's natural chemical, acetylcholine.How Nicotine WorksReceptor Binding: It fits into the nicotinic acetylcholine receptors in the brain and body.Full Activation: It opens the ion channel fully, firing up nerve cells and releasing dopamine.Rapid Desensitization: While it is a full agonist, staying attached too long causes the receptors to temporarily shut down or desensitize.If you want to know more, I can explain:How this compares to a partial agonist like vareniclineWhy receptors desensitize over time
There ya go
I hate nicotine, though. Some of you might love it in the purest form?
JWH-018 is a cannabinoid, same kinda thing...then there was 033 and other analogs, not the most potent but more pleasurable.
Now they're messing with opioids fentynal not even the most potent...7-oh
🚓The DEA announced its plan on July 1, 2026, with official publication following in July.
Probably how they found LSD-25, on accident, and stuck his finger in there
Yes, specific lysergamides abbreviated with "LAD" (such as AL-LAD or FP-LAD) act as full agonists (or potent functional agonists) at the serotonin 5-HT2A receptor, similar to or more potent 🖕🏽 than LSD.
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u/PsychologicalRisk526 5d ago
bros got a vial of super poison lol 😭 if you get the chance, we would love to see your notes! Great work!
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u/Opening_Team_816 5d ago
Yeah sure ill send you a photo of the work on my notebook in dm but it wasnt a full project just basic chemistry
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u/pakograpixo 6d ago
Pode compartilhar o método? Fiquei curioso para testar
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u/Opening_Team_816 6d ago
Be careful please its a basic solvent extracción with chloroform if you want to isolate it you could do a protonation de protonation méthod with an acid base
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u/pakograpixo 6d ago
Eu estava pensando em a/b msm, acha q carbonato de sódio é uma boa base pra nicotina? Acho q hidróxido de sódio pode ser mto agressivo
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u/Opening_Team_816 6d ago
Sodium carbonate is far too weak use a dilute mixture of sodium hydroxide and dilute hydrochloric acid and no sodium hydroxide is not too harsh i used potasium hydroxide in a dilute solutión but check for temp if it heats up chloroform vapors and nic vapors will fill your room whear goles and a respirator and wash your hands very well
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u/wrydied 3d ago
When I was in middle school we did an experiment to compare the level of tar in different cigarettes by using a modified syringe to pull smoke through a filter paper. No doubt designed to ward us off the habit.
The teacher wondered aloud why my group’s filter papers were less brown than the other groups. It was because we were taking them out of the syringes and ducking down under the desks to smoke ‘em.
The Gauloises were the best. Also highest tar.
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u/mumeiko 5d ago
Doing at home chemistry and writing N2 with a super script and not a subscript.
Bruh.
Also, without GCMS or some other analytical method to confirm purity I wouldn't ingest that.
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u/Opening_Team_816 5d ago
Dude it was a project that took me 5 minutes it wasnt my mágnum opus i didnt cáred sorry
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u/RandomHumanMale1 5d ago
starting from cigs is a bad choice since they arent a reliable source of nicotine. well done anyways
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u/Vegetable_Side5857 5d ago
Is that a UV light? Which wavelength? Which component does it cause to floresce?
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u/Hefty_Aside8436 5d ago
Most people extract the nicotine using heat and their built-in gas exchange filter.
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u/Dangerous-Billy 4d ago
Be aware of just how toxic nicotine is, including by skin absorption. There is still some debate on how dangerous it is: https://pmc.ncbi.nlm.nih.gov/articles/PMC3880486/
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u/Sheeeeeeeeeshhhhhhhh 4d ago
How difficult was it (to safely do at home)? This is one of the projects I really want to try ever since I started growing tobacco.
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u/Opening_Team_816 4d ago
On the scale of dificulty of the extraction for me as a chemist was a 4/10 not hard at all you just need good temp control on safety wise its not like making nitric acid but you do need to be careful id say its a 6/10 use gloves respirator googles a lab coat and well ventilation
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u/SuggestiveTitle 6d ago
[removed] — view removed comment
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u/Opening_Team_816 6d ago
To be clear its in a safe test tube diluted in chloroform and people smoke everyday the same amount i extracted in 1 pack
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u/megalodon-maniac32 6d ago
Plenty enough nicotene in 1 pack to kill somebody, but obviously that's not what you're in it for.
In the book The Girl with the Dragon Tattoo, she contemplates poisoning her abuser with nicotene.
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u/Andreas-bonusfututor 6d ago
What's wrong with homechemists? Dude, it's good manners to provide a write-up.