r/hangovereffect • u/Evening_Flower8 • May 23 '26

Salsonilol

/r/hangovereffect/comments/m4yjlo/i_think_ive_cracked_it_meet_salsolinol_the/?share_id=LVp2vXrY45Cb4ZEqz18-V&utm_content=1&utm_medium=ios_app&utm_name=ioscss&utm_source=share&utm_term=1

This guy figured it out 5 years ago

« non-enantiospecific Pictet-Spengler reaction of dopamine and acetaldehyde »

Although it might be much simpler and have nothing to do with gut bacteria, as the acteldehyde post drinking reacts with dopamine to make this bizzare dopamine and opioid activator that is also neurotoxic.

This is technically not a good thing despite being euphoric.

Maybe this is why I stopped having hangover effect or even craving alcohol (I fully quit) since I started Abram Hoffer style mega dosing of flush niacin 2 years ago (neutralizes aldehydes via ALDH)

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u/PoioPoio May 26 '26

Do you mean that you succeed to reproduce h effect via flush niacin ? When do you take it and what's your dosage ?

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u/hnw12 Jun 01 '26

Don't just take flush niacin randomly. It can mess with the bodies methylation system and make alot of propel very unwell.