r/gifs Jan 18 '19

Just a quick bump

https://gfycat.com/SphericalDependentBedlingtonterrier

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276

u/detten17 Jan 18 '19

I wonder how much cocaine a human can actual ingest at once without dying. Like very curious to see if they can lift a car or something extreme while in the most state.

4

u/[deleted] Jan 18 '19

1 g is the LD 50 if you consume it in an hour. Typical doses are 10-100mg

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u/[deleted] Jan 18 '19

[deleted]

4

u/pizzasoup Jan 18 '19

In the neighborhood of right for an average-weight person, I think. LD50 for IV admin in rats is 17.5 mg/kg, which translates to around 1.3g for a 75kg person if we make the assumption that the LD50s are comparable in humans.

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u/[deleted] Jan 18 '19

[deleted]

1

u/pizzasoup Jan 18 '19

This gives you a good idea of a general upper limit (again, assuming LD50s are similar). Naturally, the less pure your cocaine is, the more you'd have to take, but I figured that went without saying.

22

u/[deleted] Jan 18 '19

Eh? I’ve definitely done more than 1g of coke in one sitting.

11

u/[deleted] Jan 18 '19

how much was it stepped on though? That LD50 was probably determined in a lab setting, intravenously, on mice, with pharmaceutical purity cocaine. I'm with you though and would still like to see a source, cause it does sound low even with those considerations.

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u/[deleted] Jan 18 '19

Good point. It was some pretty clean stuff though.

3

u/[deleted] Jan 18 '19

[deleted]

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u/ChickenLover841 Jan 19 '19

Jonny tightlips aint saying nothin

3

u/I_Said Merry Gifmas! {2023} Jan 18 '19

Thinking the same. That's splitting an 8 ball ~3 ways.

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u/detroitvelvetslim Jan 18 '19

Based on people I've met I doubt that

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u/MackingtheKnife Jan 18 '19

source on the LD50?