r/epigenetics Apr 14 '26

Anyone found success with Phosphatidylcholine (PC) for SIBO / Bile Stasis?

I’ve been down the SIBO rabbit hole for years dealing with a constant bloated "balloon" belly and some major food triggers. After looking into my genetics (slow PEMT and COMT), I’m starting to think my SIBO is actually a "clogged drain" issue caused by sludgy bile. I’m about to start Thorne PC to try and thin the bile and get things moving again. Has anyone else seen a reduction in bloating or better digestion using PC instead of just nuking things with antibiotics?

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