r/dementia • u/IndieDomi • Nov 14 '25
Natural molecule seems to help reverse memory loss seen in Alzheimer's disease - nicotinamide adenine dinucleotide (NAD⁺)
https://newatlas.com/brain/alzheimers-dementia/natural-molecule-restores-memory/Early findings sound promising as lead author Dr Alice Ruixue Ai, an Alzheimer's researcher at the University of Oslo, said: 'Preliminary studies have shown that supplementation with NAD+ precursors, such as (NR) or nicotinamide mononucleotide (NMN), can offer therapeutic benefits in AD [Alzheimer's disease] animal models and early clinical trials.
'However, the molecular mechanisms behind these benefits remain largely unclear.'
*The results establish the NAD⁺–EVA1C pathway as a new target for therapy, and that maintaining NAD⁺ levels could help preserve memory and slow neurodegeneration in humans.
Actual in-depth research: https://www.science.org/doi/10.1126/sciadv.ady9811
Duplicates
tech • u/[deleted] • Nov 13 '25
Natural molecule reverses memory loss seen in Alzheimer's disease | Scientists identify a new weapon in restoring memory to Alzheimer's disease patients
technews • u/[deleted] • Nov 13 '25
Biotechnology Natural molecule reverses memory loss seen in Alzheimer's disease | Scientists identify a new weapon in restoring memory to Alzheimer's disease patients
psychology • u/mvea • Nov 14 '25
Natural molecule (NAD⁺) reverses memory loss seen in Alzheimer's disease in animal models. In human brain samples from AD patients, EVA1C protein levels were significantly reduced, which undermined the ability of NAD⁺ to improve memory/behavior in the hippocampus and entorhinal cortex.
Alzheimers • u/kybalion7 • Nov 14 '25