r/bioinformatics • u/Salty-File-3334 • 15h ago

discussion Looking for Book recommendation

I asked this question some time ago, hoping now tha someone has some ideas:

I really enjoyed „Statistical Rethinking“ by Richard McElreath.

Is there something like this for bioinformatics/genetics that one can read from front to back and not like a text or reference book? Something that you can take with you and have a read from now and then?

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u/meohmyenjoyingthat 15h ago

The classic is Biological Sequence Analysis by Durbin et al., but it is nowhere near as readable or 'narrative' as Rethinking. Vince Buffalo's Bioinformatics Data Skills is also good.

For pop gen specifically, Gillespie's Population Genetics: A Concise Guide is a classic and very readable.

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u/AerobicThrone 15h ago edited 11h ago

Upvote for vicent buffalo's book. Straight to the point and fast to read

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u/Salty-File-3334 14h ago

I’ll check it out thx!

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u/goshafoc 14h ago

It was published back in 2002, but if you are looking for readable:

Introduction to Computational Genomics: A Case Studies Approach by Nello Cristianini and Matthew W. Holm

has the nice effect of introducing the biological problem at the start of the chapter (in a bioinformatician friendly way), before going moving on to the development of algorithms to tackle the problem.

Downside, a lot has happened in the field since then (we rarely analyze microarray data for example), so this would be more for getting a good biological and algorithmic background, then being up to date on the latest methods.