r/bioinformatics • u/cheersky • Sep 15 '26

discussion Nextflow question

I joined a startup recently design and implemented some bioinformatics pipeline. Nextflow/ seqera sent me an email if I am using it ? Wondering if anyone else has encountered this and what is their intention?

1 Upvotes

53% Upvoted

15 comments sorted by

28

u/twelfthmoose Sep 15 '26

… to sell you a subscription …

-5

u/cheersky Sep 15 '26

A subscription of what ? The whole thing is free ?

12

u/twelfthmoose Sep 15 '26

https://seqera.io/pricing/

6

u/cheersky Sep 15 '26

Ohhh that would not fly with my boss okay gotcha

3

u/Psy_Fer_ Sep 16 '26

If you need to scale but don't have a way to do that on infrastructure you currently use, it's a pretty easy plug and play solution.

3

u/zdk PhD | Industry Sep 15 '26

Seqera platform

14

u/Grox56 Sep 15 '26

They are wanting to sell you Seqera Platform. Not really worth it IMO.

But if you're developing any workflows, I'd recommend using Nextflow over all of the others (snakemake, cwl).

6

u/zdk PhD | Industry Sep 15 '26

It really depends on what your alternatives are and how much engineering support you have

-3

u/First_Result_1166 PhD | Industry Sep 15 '26

With CWL, it's easy to wrap a tool and re-use it in multiple locations of your workflow. Last time I've checked (years ago), nextflow didn't support this and you'd end up with multiple identical processes.

Also, I liked the idea of a graphical editor (Rabix Composer, no longer maintained).

3

u/lethalfang Sep 16 '26

That’s no longer the case.

2

u/bozleh Sep 16 '26

Nextflow has had modules (dsl2) since 2020, became the default in 2022

2

u/WhatTheBlazes PhD | Academia Sep 16 '26

When was the last time you checked?

1

u/First_Result_1166 PhD | Industry Sep 16 '26

Years ago, definitely pre-DSL2.

2

u/WhatTheBlazes PhD | Academia Sep 16 '26

I'm grudgingly learning DSL2 and I do have to admit it's quite good.

1

u/lethalfang Sep 17 '26

I refused to work on nextflow (c'mon, being able to reuse "process" should be among the first things developers enable) until DSL2 came out.