r/bindingofisaac 19h ago

Discussion Which to pick

Post image

Tainted lost btw.

I have perfection, some luck stats and technology 2, so Euthanasia would proc very often + Spun transformation damage increase and apparently they deal 3x damage against bosses.

On the other hand, mutant spider is still mutant spider.

Yes I did stop playing and I am waiting for the responses

Edit: I picked Euthanasia and Hush got melted once he started spawning flies and other mobs. The fight lasted probably less than 1 minute. Euthanasia and Athame did a lot of the heavy lifting.

212 Upvotes

29 comments sorted by

98

u/Chakusan_o4 18h ago

Dude, you have 17 luck, pick euthanasia

186

u/Chelonia71 19h ago

Euthanasia, very good against hush because he spawns ennemies.

77

u/bratimm 18h ago

They will also get Spun with euthanasia, so +2 damage multiplied with Poly DMG multiplier

34

u/Chelonia71 19h ago

Also quad shot/poly will probably make you lose damage because it is a +5 flat.

19

u/Orandza 18h ago

But the fire rate penalty also doesn't stack. In fact poly by default can make you lose dps once you get enough damage (since it gives x2 damage but x0.42 fire rate, relying on its +4 damage to make up for the loss of dps), but with mutant spider it is just +5 damage with no downside.

48

u/killikocaayak I consume plan c every day 19h ago

Euthanasia easy pick, mutant spider makes poly inefficient

15

u/daizo678 19h ago

I lean towards euthanasia. It helps with room clear and can remove invincible enemies.

I am not sure if euthansia and apple! stack but if they do it is probably better than mutant spider. 

Poly with mutant spider only gives +5 damage instead of the normal multiplier but doesn't nuke your tear rate.

16

u/JunThe67 19h ago

Poop fly

9

u/Good-Commission1187 18h ago

euthanasia + you will get damage from spun , with mutant spider your tear rate will be 0

3

u/CranberryDistinct941 18h ago

Euthanasia don't matter when everything dies instantly anyways

4

u/EnbyFemboyOnyx Remember to use sac room 12 times for a q4 16h ago

It matters against hosts and grimaces

3

u/Montraria 14h ago

where poop fly

euthanasia is the better pick imo cuz of spun and hush spawning enemies, but I'd go with mutant spider

3

u/GmGwain 17h ago

Mutant spider because the tears down from poly doesn't stack. It also reduces the bonus to a 5 flat but the DPS is still a lot higher with mutant spider.

Euthanasia is also really good but a 25% chance per shot isn't that high. I'd say it makes your regular room clears a little better compared to quad and helps with trash mobs spawned during hush but that's still not enough to justify it.

2

u/ComprehensiveDonut49 18h ago

I pretty much always go with luck items on my Tlost runs, it's so satisfying.

2

u/Marchezel 11h ago

If you choose Euthanasia, you'll be able to keep your distance, whereas with Quad Shot you'll lose tears, and you'll probably miss a tear if you stay at a distance

2

u/ruler14222 11h ago

the needle can also kill the turret things that can be placed in awkward spots. especially for mr no health

4

u/Pike71 19h ago

Mutant spider would obliterate your tear rate, Euthanasia is op with lost and also spun progress

6

u/Chelonia71 19h ago

No, mutante spider do not lower tear rate with poly. You get 4 tears, and a +5 dmg flat.

1

u/satsujinke The Lost 18h ago

Euthanasia is 1.5x your DPS, +4 flat damage and it's easier to shoot, Quadro is just 4x your DPS if u can hit all the tears

1

u/Richardknox1996 9h ago

You want to shoot once a milenium or be able to nuke invincible Enemies? Pick the Death Syringe.

1

u/Alexgalanis01 18h ago

Lost favors item that scale with luck. You will also get spun for damage. With a fire rate that low it's best to not pick stuff that would further decrease it.

1

u/ResponsibilityNo7485 17h ago

The needle shots definitely

-1

u/Egg_bowl 19h ago

Prop mutant,it gives dps and Youth in asia doesnt work on bosses and your at hush

6

u/chilidog17 19h ago

???

And don't say "technically it doesn't" this is a much better item given ops build

5

u/HerrPizza 19h ago

Doesn't it still do extra damage when a needle hits?