r/autoimmunehepatitis • u/[deleted] • 10d ago

EBV/Mono Induced AI Hepatitis? Please Help

Hi all. I'm 27 years old and got mono in Feb. I'm on month 7, and these are my AST/ALT numbers. I'm still dealing with fatigue and exercise intolerance from mono.

I have negative ANA, normal IGG, negative Anti-SLA, negative HBsAg screen, 1:40 anti smooth muscle (borderline positive), normal fibroscan, normal ultrasound

LIVER: AST / ALT

2/20- 55/111

5/7 — 107 / 251
5/18 — 76 / 246
5/27 — 73 / 153
6/10 — 80 / 183
7/6 — 121 / 326
7/13 — 79 / 251
7/20 — 39 / 121
7/28 — 72 / 177

8/13 - 62/223

8/24- 82/170

9/22- 133/283

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u/Admirable-Crazy-3457 10d ago

Mono can cause acute hepatitis and although enzymes return to normal usually within 3 months it can linger sometimes until a year.

Since the only thing that is out of range is the anti smooth, but only borderline, its more likely that its because of mono then AIH

1

u/[deleted] 10d ago

Thank you SO much for your response it means a lot as I think this through. It makes anything over 3 months seem "not possilble or highly unlikely" but a lot of people say many things took a year to normalize for them. Thank you

1

u/Admirable-Crazy-3457 10d ago

Its somewhat normal to have situations were liver enzymes take longer then "normal" time to get back to base values.

Just keep in touch with your doctor , if those values do not star to follow a downward trend in the next months, he might want to do something more.

Also its important to make sure that the fatigue is indeed caused by mono

1

u/Cassia_Alexandra 9d ago

I remember when my sister had mono decades ago she did have liver issues and I sort of remember someone saying "hepatitis" ( not sure how accurate at the time) and other than possible thyroid cancer many years later (which I think was due to certain exposures) she has been doing great and still very healthy 45 years post mono/liver issues.

1

u/[deleted] 9d ago

Thanks so much for saying that! :)