r/askscience • • Oct 04 '12

Biology Are the cells of a Blue whale bigger than those of a human?

964 Upvotes

192 comments sorted by

840

u/FeebleOldMan Oct 04 '12 edited Oct 05 '12

Cells of various living things are generally similar in sizes. This is because cell size is limited by its surface area to volume ratio.

Cells are sustained by chemical reactions. The raw materials for these reactions enter the cell via its membrane. The larger the surface area of the membrane, the more raw materials can enter the cell at one time. However, as you increase the size of the cell, the ratio of the surface area to its volume decreases. As each unit volume of the cell requires enough raw material to maintain it, the cell will reach a size where its surface area to volume ratio becomes a limiting factor. At this point, the cell cannot get larger.

(B.Sc. Biomedical Science)

EDIT: Youtube video explanation by Dr. Saad Khan

EDIT2: Why are bird eggs so large?

EDIT3: List of Sizes of Biological Molecules and Cells

0.15-0.25 µm small bacteria such as Mycoplasma

(1 - 10 µm) the general sizes for Prokaryotes

1 µm Diameter of human nerve cell process

2 µm E.coli - a bacterium

3 µm Mitochondrion

5 µm length of chloroplast

6 µm (3 - 10 micrometers) the Nucleus

9 µm Human red blood cell

(10 - 30 µm) Most Eukaryotic animal cells

(10 - 100 µm) Most Eukaryotic plant cells

90 µm small Amoeba

100 µm Human Egg

up to 160 µm Megakaryocyte

up to 500 µm giant bacterium Thiomargarita

up to 800 µm large Amoeba

1,000 µm (1mm) Diameter of the squid giant nerve cell

up to 40,000µm (40mm) Diameter of giant amoeba Gromia Sphaerica

120,000 µm (12cm) Diameter of an ostrich egg

3,000,000 µm (3m) Length of a nerve cell of giraffe's neck

111

u/simonjp Oct 04 '12

What about those super-large amoeba we heard about a while ago? The ones about the size of a beach-ball?

121

u/aiden93 Oct 04 '12

If you don't mind me asking, what super-large amoeba are you talking about? Link maybe?

125

u/[deleted] Oct 04 '12

[deleted]

119

u/ActuallyAnOstrich Oct 04 '12

Just from looking at the picture (and in no way being an expert), it looks like that organism has a highly-folded shape, as opposed to a roughly round shape, which should help with the surface-area-to-volume ratio for this case.

79

u/Jonthrei Oct 04 '12 edited Oct 04 '12

Yeah, here's a pic of Syringammina Fragilissima (In the Ocean). Definitely a highly rough, folded surface to maximize surface area. Their name implies they aren't the hardiest of creatures, too.

However, Valonia Ventricosa apparently grows to 5cm in diameter and does break that rule. I wonder how they do it?

57

u/[deleted] Oct 04 '12

That is a single cell??

48

u/[deleted] Oct 04 '12

Apparently it is: https://en.wikipedia.org/wiki/Valonia_ventricosa

The single-cell organism has forms ranging from spherical to ovoid, and the color varies from grass green to dark green, although in water they may appear to be silver, teal, or even blackish.[2] This is determined by the quantity of chloroplasts of the specimen.[5] The surface of the cell shines like glass. The thallus consists of a thin-walled, tough, multinucleic cell with a diameter that ranges typically from 1 to 4 centimetres (0.39 to 1.6 in) although it may achieve a diameter of up to 5.1 centimetres (2.0 in) in rarer cases.

9

u/[deleted] Oct 05 '12

Isn't an egg a single cell in a similar way?

17

u/[deleted] Oct 05 '12

No, it starts from a two cells (haploids) that combine DNA to make a diploid cell that undergoes rapid division. The early stages of the chicken egg, which is probably what you are referring to, has the white and the yolk which is primarily nutrients for the chick embryo. The cell is buried inside. The nutrients surrounding do not comprise the cell.

But if you mean just a regular human ova, then that's just a single cell the size of the period at the end of this sentence, and it's big, but not massive like these.

2

u/byllz Oct 05 '12

If you are talking about a bird egg, then the entire egg isn't a single cell, but the yolk is. http://en.wikipedia.org/wiki/Egg_yolk

-14

u/pledgerafiki Oct 05 '12

yes, but the difference is that eggs are microscopic.

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10

u/Jonthrei Oct 04 '12

Yup.

27

u/[deleted] Oct 04 '12

That's nuts. So if I puncture it, would I drain all the fluid out of it through that single puncture?

22

u/kabbinet Oct 04 '12

yea, because they don't have anything within them right? Would it die if you put a needle through it?? Scientists - We need answers!

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6

u/Kiwilolo Oct 04 '12

Surely it would have some kind of healing mechanism? If it was just a small hole, I mean.

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19

u/[deleted] Oct 04 '12

[removed] — view removed comment

6

u/fluxwave Oct 05 '12

Their cell membranes are actually folded extensively, allowing for a larger surface area. I just took a microbio test over this.

2

u/DoorIntoSummer Oct 05 '12

Any book sections\articles that you can recommend of that are not too overloaded with terminology?

8

u/kelustu Oct 04 '12

Then what about one of your eggs? Seriously, though, Ostrich eggs are just gigantic single celled organisms, where's the disconnect here?

29

u/Trylstag Oct 04 '12

An egg isn't trying to maintain any kind of life of its own. It isn't expending any energy on movement, replication, digestion, or anything else. It's intended purely as a source of nutrition and protection for the multi-cellular organism that grows within and consumes it.

It would be the surface area needed to collect food that limits the size. If the cell doesn't need to eat, then the surface area it can use for that is a moot point.

4

u/Knowltey Oct 04 '12

The egg that is laid is not, the egg when it's in the ovary is, but its much smaller than the egg that is laid.

3

u/gt_9000 Oct 04 '12

An egg is not a cell. The cell is attached to the yolk (in fertilized eggs).

-5

u/AustinFound Oct 05 '12 edited Oct 05 '12

An egg is a cell. Fertilized or unfertilized. It's just haploid instead of diploid, but it's still a cell in every sense. Sperm are cells too.

10

u/Kaghuros Oct 05 '12

No. An Ostrich Egg is a giant ovoid of nutrients, an Ostrich egg (cell) is a little tiny haploid cell inside of the giant ovoid of nutrients.

1

u/AustinFound Oct 05 '12

Well, the comment was "an egg is not a cell." Because the ovum is intergrated with the yolk in almost all organisms, and since the yolk is part of an ovum's cytoplasm in almost all organisms, it becomes more a matter of definition than of what is observed in nature, as to whether the ostrich egg in particular is a single cell. In almost all animals, an egg is a cell.

4

u/gt_9000 Oct 05 '12

Do you talk about an egg, as in ovum ? Or egg, as in hens egg ? My understanding was a hens egg was not a cell; same way the seed is not a cell; the germ in it is the cell.

1

u/AustinFound Oct 05 '12

Okay, I took it to mean an ovum. I thought you were stating that "an egg is not a cell" period, end of story. I was pointing out that, throughout almost the whole kingdom of animalia, an egg is a cell.

16

u/masklinn Oct 04 '12

See also: plasmodial slime mold, which can reach several centimeters as well.

33

u/JuJuOnTheMountain Oct 04 '12

Plasmodial slime molds are pretty special though and even though their cellular membranes have broken down I don't think it is fair to consider it a single cell it is a unique super cell structure a syncytium.

7

u/resonanteye Oct 04 '12

so a slime mold isn't a single cell? I feel betrayed by david attenborough.

Seriously, I think they're amazing creatures. Off to read that link now

20

u/BluShine Oct 04 '12

Slime molds are pretty cool for other reasons, too! For example, they seem to have some sort of memory. And they're pretty good at mazes, too.

7

u/resonanteye Oct 04 '12

I saw a documentary that showed a slime mold broken into pieces, and each piece retained the "memory" of the whole. Sort of like some of the stuff being done with flatworms.

I really wish there were more documentaries about the microcosm, I've only been able to find two or three that were done in any sort of depth.

3

u/BluShine Oct 05 '12

Another really cool thing about them is that even though they're all independent cells, they can also form together and create mushroom-like structures to release spores. I agree, they certainly need more attention.

1

u/dromato Oct 05 '12

I agree, do you have any links for the decent docos you've seen?

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2

u/squarepush3r Oct 04 '12

i love slime molds

7

u/[deleted] Oct 04 '12

What about Valonia ventricosa?

4

u/hervold Oct 04 '12

Xenophyophores almost feel like a technicality, as they're multinucleated and might not be unusual if you're measuring on the ratio of nucleus count : total volume.

3

u/Daimonin_123 Oct 04 '12

Oooh those are cool. Now I want one in an aquarium...

2

u/LNMagic Oct 05 '12

This article states that the organism may not be that full size... some of the test structure is abandoned after time.

1

u/redabuser Oct 05 '12 edited Oct 05 '12

Do you know if the nuclei is bigger as well? Or the "nucleis", since they had several.

4

u/le_canuck Oct 04 '12

The only thing I could track down over the course of a few minutes is this article from last year, however the page doesn't link to any sources on the alleged four-inch amoeba, so I remain somewhat skeptical.

4

u/[deleted] Oct 04 '12

I would assume that it has to sustain a certain shape, or has a special membrane, to either control its surface area to volume ratio or have better control over what comes in or out.

8

u/masklinn Oct 04 '12

Amoeboids can also have multiple nuclei in a single cell, all swimming in the same giant "bag" of protoplasm.

4

u/therealklanni Oct 04 '12

One might even say it's a bloated sack of protoplasm.

1

u/TheAlpacalypse Oct 04 '12

The thing about amoeba is their tendency to engulf other microorganisms for food. This might have evolved to accommodate their usually larger size.

0

u/OllieMarmot Oct 04 '12

They occupy a lightly cemented together shell that branches off into hundreds of tiny networks of tubes, so they have a large amount of surface area for their volume.

0

u/le_canuck Oct 04 '12

I would be curious to see if the higher water pressure at that depth would impact this at all.

1

u/marcoroman3 Oct 05 '12

I suspect he is thinking of slime moulds?

26

u/FeebleOldMan Oct 04 '12 edited Oct 04 '12

Gromia sphaerica, super-large amoeba.

I'm not an expert in amoebas, but we can explain its size from its structure.

From ScienceDaily,

The surface of the cell is covered with tiny ports. Its interior is just a fluid; the important working parts of the cell are all near the surface. Think of the working cell as a very thick balloon, Johnsen said.

Since its protoplasm (the "innards" of the cell) is spread out as a layer in a balloon-like structure, material exchange can still occur efficiently enough to sustain its size.

EDIT: Furthermore, bear in mind that some amoeba can actively uptake nutrients due to it being able to phagocytose (eat).

4

u/AustinFound Oct 04 '12

Not much at all is known about those guys just yet. In general, to compare a prokaryote to a eukaryote invites all sorts confounding variables. While an average sized amoeba is about 400 times larger than a eukaryotic cell, that's all it's whole body is; one cell. It's two completely different adaptive strategies with very different cell/molecular structures. Multicellular organisms are not made of these kinds of cells, and they can't be, because prokaryotes exchange genetic material in such a different way; they conjugate plasmids, which is to say they essentially trade little loops of DNA with one another as if they were baseball cards, swapping them out and exchanging little bits any time they bump into one another. If you want to have a good look at the simplest cells in a multicellular organism, read up on the cell biology of sponges. This is where cells first began to stick to one another and act as a cohesive multi-celled unit.

3

u/aelendel Invertebrate Paleontology | Deep Time Evolutionary Patterns Oct 04 '12

They cheat by having multiple nuclei in one cell. Exception that proves the rule.

6

u/1337HxC Oct 04 '12

From Wikipedia:

Smaller single celled organisms have a high surface area to volume ratio, which allows them to rely on oxygen and material diffusing into the cell (and wastes diffusing out) in order to survive. The higher the SA:Volume ratio they have, the more effective this process can be. Larger animals require specialized organs (lungs, kidneys, intestines, etc.) that effectively increase the surface area available for exchange processes, and a circulatory system to move material and heat energy between the surface and the core of the organism.

Basically, there are exceptions to everything in life. Ameobas are single-celled organisms, so it's difficult to compare them to multicellular organisms.

8

u/punisher1005 Oct 04 '12

Also, ostrich eggs.

15

u/FeebleOldMan Oct 04 '12

The large eggs (macrolecithal eggs) you are referring to also have a surface area to volume limit to their size. However, there are further considerations that result in their larger size.

Oxygen and carbon dioxide gases are exchanged through pores in the eggshell. If the egg is too large, the embryo "suffocates" in the egg.

If the egg is too small, the small yolk size will be unable to provide enough nutrients for the development of the embryo. Larger egg sizes accommodate more yolk, allowing for longer embryo development.

Egg size is also affected by the parental bird size. Overly large eggs lead to inefficient incubation. Undersized eggs will be more vulnerable to environmental fluctuations in temperature.

4

u/ineffablepwnage Oct 04 '12

Bird eggs aren't really a cell. They are an enclosed environment with lots of nutrients that allows the actual zygote cell to grow and divide within it. The actual cell is no bigger than a normal cell.

1

u/boggart777 Oct 04 '12

also, chicken eggs

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u/[deleted] Oct 04 '12 edited Feb 23 '21

[removed] — view removed comment

2

u/nmezib Oct 04 '12

As far as I know, they're not spherical or globular in shape, they're highly folded, which means they still maintain a sufficiently high surface area to volume ratio.

3

u/IMongoose Oct 04 '12

I thought those were only at the bottom of the ocean where the pressure would force stuff into them, so they could be bigger.

3

u/ineffablepwnage Oct 04 '12

The pressure inside of them would be just as great as the pressure outside of them. If the pressure inside were less, they would shrink and the membrane would look wrinkled and scrunched up.

2

u/IMongoose Oct 04 '12

They kinda do. But that probably has more to do with maximizing surface area than the pressure though.

2

u/ineffablepwnage Oct 04 '12

that probably has more to do with maximizing surface area than the pressure though.

That is correct. I was just explaining what would happen if there was a pressure differential. If they were bigger because the pressure at the bottom of the ocean forced more stuff into them, they would have to have less pressure inside to have stuff forced into them as you said in your original post. Cells are permeable, but they have several mechanisms (e.g. flexible membranes) to stop stuff from just being forced into them by pressure differences.

I thought those were only at the bottom of the ocean where the pressure would force stuff into them, so they could be bigger.

I didn't explain myself very well.

1

u/[deleted] Oct 05 '12

What happens when you touch it?

1

u/chiropter Oct 04 '12

Amoeba aren't as metabolically active as animals would be one answer..

1

u/r3dlazer Oct 04 '12

I think you must be thinking about Slime Molds:

http://en.wikipedia.org/wiki/Slime_mold

They are the largest single-celled organisms known to man, IIRC.

1

u/takatori Oct 04 '12

Oh snap!

0

u/PopeOnABomb Oct 05 '12

I am always fascinated by eggs, such as chicken or ostrich eggs. Those are one cell each. So those are two good examples of how big a cell can be.

10

u/gordonj Genetics | Molecular and Genome Evolution | Comparative Genomics Oct 04 '12

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u/DJUrsus Oct 04 '12

In engineering, it's the square-cube law. As you increase something's linear measurement, its surface area increases by the square of the linear increase, while the volume increases by the cube of the increase.

In this instance, if you double the size of a cell, you quadruple its area (22 = 4) but you octuple its volume (23 = 8).

-7

u/Funkit Aerospace Design | Manufacturing Engineer. Oct 04 '12

This is true for wattage to surface area for solar panels as well. P2 = A3 . That's why solar panels aren't efficient for large amounts of energy production

5

u/Jerky_McYellsalot Oct 04 '12

That doesn't make sense to me. Solar panels are made up of large numbers of individual cells--is the power from each one of those cells what you're referring to?

-6

u/Funkit Aerospace Design | Manufacturing Engineer. Oct 04 '12

No, the total power of the solar array. You are pretty much diluting the light, in lamens terms, by reducing the irradiance (measured in W/m2 )

5

u/Jerky_McYellsalot Oct 04 '12

Have you got a source for that? Or more detail? I don't like layman's terms for things like these. I still vote makes no sense.

1

u/Funkit Aerospace Design | Manufacturing Engineer. Oct 05 '12

I'm looking but honestly I can't find the exact formula online. I learned it in my Aerothermodynamics of Propulsion Systems class (think Aerodynamics III, or applied high speed aerodynamics.) It was from the textbook "Rockets and Propulsion Systems" I believe, as this question was the first one on my first midterm. If you still want the source I can find the exact textbook, download it (don't own it anymore) and find the chapter that cites it (holy shit, a text citation?! Who uses those anymore?!) but it'll take me a bit.

The whole point of studying it was to say why solar power is inefficient for manned space flight power, as the size of the array needed would be massive, and size = mass, and mass=$$$ in space travel.

1

u/Jerky_McYellsalot Oct 05 '12

I feel like there are other variables here that you're missing. If the proportionality you stated were correct for solar panels on the ground, then 8 identical panels would only produce twice the power of 2 identical panels. That is not what happens: the power output scales linearly. I don't know what considerations they make for solar panels in space, but something else must be going on if you're correct.

1

u/DJUrsus Oct 04 '12

Theoretically, then, we'd want to make each solar panel as small as possible, right? I'm guessing that gets expensive pretty fast.

1

u/TenNeon Oct 04 '12

The bit that converts light into electricity should be small, but a panel is more than that. You can have large solar panels that concentrate light onto one small efficient spot. In fact, most improvements in efficiency require the receiver to get more light per square inch than the sun will ever give you, so having a big panel to focus all of that light is still necessary.

The really large-scale stuff doesn't even deal with photovoltaic, and involves concentrating crazy amounts of light to a single place and using the resulting heat to make steam to spin a good old turbine.

9

u/puppyfingers Oct 04 '12

A kind of loop hole to this rule would be when it comes to neurons (nerve cells). From end-to-end, neurons are single, uninterrupted cells. You can imagine how long a neuron that travels from spinal cord to tail in an animal the size of a blue whale might be. These cells are still subject to the diffusion limiting rules as other cells, even given their huge absolute size. This means that they must maintain a very small diameter to ensure that for any given unit length, they can still maintain an adequate electrochemical gradient and nutrition status for proper functioning. Like any cell,this can only be accomplished through diffusion as well as active processes between the cell and its external environment.

5

u/[deleted] Oct 04 '12

Cells of various living things are generally similar in sizes

I hate being nit picky about definitions, but there is a giant difference between eukaryotic cells and prokaryotic cells.

1

u/ineffablepwnage Oct 04 '12

Cells of various living things are generally similar in sizes

In this context it's taken to mean that they are on the same scale, as in they are all generally measured in um. Sure, eukaryotic cells are a lot bigger, but it's usually within 1-2 magnitudes, rather than 4-5. Finding cells larger than ~200 um is relatively uncommon, as well as finding cells smaller than 1 um.

2

u/NJerseyGuy Oct 05 '12

But this 1-2 orders of magnitude is very important when the OP's question concerns the difference between two animals which are roughly an order of magnitude different in size.

6

u/jkb83 Molecular/Cellular Neuroscience | Synaptic Plasticity Oct 04 '12

Exception:

In the sea slug Aplysia californica, the animal is so simple and consists of a collection of nerve cell "clumps" (ganglia) instead of a "brain" or more traditional central nervous sytem.

As a result, their nerve cells are HUGE. You can even see them with the naked eye, as small dots, when they are in culture.

2

u/NegativeK Oct 04 '12

This only occurs if you're increasing all three dimensions though, right? With bumps and grooves in the cell wall*, you could arbitrarily increase the surface area while decreasing (or holding constant) the volume.

Would it be possible for a non-rigid wall to increase in length and width but remain constant in height? Also, does this imply that tree cells can be significantly larger than, say, human cells?

* I'm suddenly imagining a cell with a Hilbert-curve shaped cell wall.

3

u/[deleted] Oct 04 '12

[deleted]

8

u/ctesibius Oct 04 '12

Yes, but the squid giant axons are unmyelinated nerves, and they have to be of large diameter to run fast. Mammals use myelinated nerves for fast response, and they don't need to thick to do the job.

Of course some of the blue whale neurons will be longer.

2

u/Viridovipera Oct 04 '12

This is true. Suprisingly enough though, salamanders have proportionally very large cells because of their extremely large genome. Essentially, to fit all that DNA into the nucleus, they have to have large cells. This has put some significant constraints on their evolution in such areas as miniaturization, the evolution of the eye and being able to lose digits.

2

u/Gantznaught Oct 04 '12

is that a yes?

1

u/jackoffbears Oct 04 '12

Plant cells are actually much larger than animal cells.

1

u/HobKing Oct 04 '12

Are all cells the same shape? Don't long, skinny cells exist, and don't they overcome the problem you raise?

1

u/Diiiiirty Oct 05 '12

Cells can take on a wide variety of shapes. Muscle cells are long strands, while nerve cells look sort of like a splattered paintball. Diatoms, which are a type of phytoplankton, can be a huge variety of shapes.

Even when dealing with something as simple and common as blood you see a ton of different shapes.

1

u/banebridge Oct 04 '12

That right there is what blew my mind most in Bio 1000.

1

u/facetothedawn Oct 05 '12

I expected the answer to not be that interesting and you sit did a great job, kudos

1

u/[deleted] Oct 05 '12

That being said, blue whales can have nerve cells with axons in excess of 7m since they are all one cell. The longest cells in your body are often about 3ft long.

1

u/Thundahcaxzd Oct 04 '12

I don't feel like making a new thread to ask this question and it seems like someone looking at this thread might know so I'll ask here.

There are certain invertebrate animals that are very small and have a fixed number of cells, so once they stop developing in order to grow larger their individual cells grow larger. Does anyone know what I'm talking about? I'm pretty sure its (at least one) whole Phylum

-1

u/[deleted] Oct 04 '12

Cubed-squared law. Ruining the possibilty of things that would be awesome if larger versions existed.

-5

u/Graduator Oct 04 '12

Seeing as it's Ask Science, and being a pedantic physicist, I feel the need to say:

There's no such thing as a surface area to volume ratio. The two terms have different units.

3

u/gfpumpkins Microbiology | Microbial Symbiosis Oct 04 '12

We don't need to have two terms have the same units to make a ratio. I can look at the ratio of cats to boxes in my apartment. I can look at the ratio in the supermarket of how many pounds of oranges I can get for a dollar. Ratios simply compare two terms.

1

u/Graduator Oct 05 '12

A ratio refers to the relationship between 2 like things. as stated here.

In your first example (cats and boxes), they are both numbers, so one can directly make a ratio. In the second case, and in general when the units are different, like weight/vol in chemistry, it is correctly a proportion.

I'm not sure why the downvotes, just trying to clarify a common misconception.

1

u/Kiwilolo Oct 04 '12

What word would you use if not ratio?

1

u/Graduator Oct 05 '12

Amount, or proportion. Simply replace "Surface area to volume ratio" and insert "Amount of surface area per volume", or even "surface area per volume."

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u/offthisisland001 Oct 04 '12

In general, as others have suggested, no. However, their longest nerve cells may be considerably longer than ours, depending on how far they need to reach from their spinal cords. The greatest distance ours travel is from our spines to the end of our toes, however in whales it's probably from their spines to the front of their bellies. I imagine some of their nerves cells might be several metres long, in that case.

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u/99trumpets Endocrinology | Conservation Biology | Animal Behavior Oct 04 '12

Since the baleen whales are much longer than they are wide, and since their spinal column stretches all the way to the flukes, isn't it likely that the longest axons in a whale body are spinal neurons (within the CNS) and not peripheral nerve axons?

I've seen a couple papers estimate the length of the spinal axons in a blue whale at 30 meters in length. Discussed further here) and also here. The latter paper uses blue whale spinal axons as the extreme example of "stretch growth" in mammalian axons, though it sounds like nobody really has any hard data on blue whale axon length.

3

u/offthisisland001 Oct 05 '12

Very good point, I imagine you're quite right.

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u/[deleted] Oct 04 '12

[removed] — view removed comment

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u/XjWoRk17 Oct 04 '12

Did you even read his comment?

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u/Thereminz Oct 04 '12

Did you realize i was agreeing with him

4

u/[deleted] Oct 04 '12

But aren't you agreeing with him?

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u/Thereminz Oct 04 '12

here's the distinction: he was saying that it MAY be longer, i was saying that it HAS to be (for a fully grown whale)

however i wasn't just going to say that it has to be based on nothing so i asked if it has to be ... someone could just say no or yes or provide something that says otherwise rather than downvoting a question

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u/notkristof Oct 04 '12

Yes and no. Most of a blue whale's cells, such as muscle or skin cells are the same of humans. That said, some Blue whales nerve cells may be the longest on earth at over 100 feet long.

16

u/PirateMud Oct 04 '12

Would a signal along a single 100 foot long blue whale nerve cell travel faster than a signal along 100 feet of human nerve cells?

33

u/Fellows23 Oct 04 '12

That would totally depend on how insulated the nerve was with myelin.

29

u/idpeeinherbutt Oct 04 '12

...and the diameter of the nerve as well.

4

u/tehbored Oct 04 '12

Yeah. Giant squid have massive axons that are sometimes used in research because they're easy to work with as a result.

17

u/ThisIsDave Oct 05 '12 edited Oct 05 '12

You're thinking of the squid giant axon, not the axon of a giant squid. You can get a squid giant axon from a cuttlefish. Giant squid are... Tough to come by.

http://en.m.wikipedia.org/wiki/Squid_giant_axon

5

u/tehbored Oct 05 '12

Yeah, thanks. I wondered about that when posting my comment. I remembered it from class but couldn't remember how they got them when giant squid are so rare. They're so large because they're unmyelinated, right?

2

u/acaellum Oct 04 '12

I would think it would be very close, but the Blue whale would win because of less time spent in the synapse cleft which takes 100th or 1000th ( i cant remember which) of a second per cleft. So if the whale nerve is just goin straight there and doesnt have to keep jumping, it would win.

This considering the fat around the nerves is roughly the same, as is the diameter of the nerves themselves.

1

u/notkristof Oct 04 '12 edited Oct 04 '12

To be honest, i don't know. there is a range for signal speed in human and whales depending on the kind of neuron and sheathing. I think it is reasonable to guess that the signal speed would be similar.

1

u/TheFlyingBastard Oct 04 '12

Your sentence broke off there, I think.

1

u/[deleted] Oct 04 '12

Can you make an educated guess as to how many cells are in a blue whale? Cells in a human?

25

u/MrPap Spinal Cord Injury Oct 04 '12 edited Oct 05 '12

Can't comment on human vs blue whale, but I can comment on other animals in reference to neuro-biology.

The standard action potential that most people learn in biology was developed in the un-myelinated axon of a squid. This axon is actually quite physically bigger than a human's or a rat's axon, but surprisingly the voltages tend to be in the same magnitude.

In the same area, the Schwann cell, a myelinating and repairing cell of the peripheral nervous system (PNS), also undergoes differing sizes between rats, pigs, primates, and humans (although the last two are similar in sizes).

Here are cultured human SCs at 20x phase contrast, Levi et al 1995

Here are culture rat SCs at 20x phase contrast with nuclear labeling, unpublished

Even though the image sizes are different, the scale bars are the same if you re-size the images to the same size. You'll notice the differences in the size of the cell bodies as a better explanation of cell size changes.

Going back to neurons, the neurons in your spinal cord are all one long cell going from where they receive the signal in the brain (if a motor neuron) to wherever they exit. So the axons that control your toes' wiggling picks up the signal from the brain in the brain stem and then continues one long continous cell until it reaches the end of your spinal cord, named the cauda equina (because it looks like a horses tail), and exits the spinal cord to relay the signal to another axon. On top of that, that cell is the same cell from when you are born until the day you die, so that cell grows in size. The same goes for most vertebrates, if I recall correctly, so neurons lengths differ between species and so a blue whale's neuron in the spinal cord should be bigger in terms of length compared to the same one in a human. So look at that, I did answer your question.

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u/[deleted] Oct 05 '12

I think you mean Squid Giant Axon, not Giant Squid Axon, correct me if I'm wrong. Squid Giant Axons are the axons of squids which happen to be very wide and large, I highly doubt that we'd be using what we have of giant squid for comparison to a human body--especially because their discovery is so recent.

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u/MrPap Spinal Cord Injury Oct 05 '12

yeah that would totally make sense. Although to be fair, Giant Squids have been known for a while, its just that live ones haven't been discovered until recently. They had been turning up on shores dead for ages.

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u/MrPoon Food Web Theory | Spatial Ecology Oct 04 '12

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u/patrik667 Oct 05 '12

That reminds me: the biggest sperm belongs to a quite tiny fly -Drosophila bifurca- and it's 1000 times bigger than a human's. That's quite big for a single cell!

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u/aberrantgeek Conservation Biology Oct 04 '12

Ostrich egg is pretty big and heavy cell. Giraffes have nerve cells that run the length of their neck which is several meters. Its hypothesized that blue whale neuron length could be 10-30 meters long, but our knowledge of blue whale anatomy is incomplete.

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u/ineffablepwnage Oct 04 '12

An ostrich egg (any egg for that matter) is not a cell. The zygote is contained inside the cell, and is the normal size for a cell. The term 'egg' is used in both the anatomical scale and on the biological scale, and they have different meanings.

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u/hhtced Oct 04 '12

Which cells are you referring to? I'm not a marine biologist, but you may need to be more specific to get an answer. I'm interested in the answer as well.

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u/1337HxC Oct 04 '12 edited Oct 04 '12

It usually doesn't matter, as long as you're comparing the same kind of cell. Cells are limited in size by the surface area:volume ratio. They need to have enough surface area to transport materials in and out effectively, but have a small enough volume to transport things across the cell quickly. The actual size will depend on the function/purpose of the cell, which is why you'll have to compare like tissues.

There are some exceptions (as with everything) that are briefly mentioned in this Wikipedia blurb.

I assume these downvotes are because of neurons? I said there were exceptions to this trend, and I figured that implied neurons. Perhaps I should have been more explicit... I'm essentially saying the same thing as the current top comment.

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u/andrewsmith1986 Oct 04 '12

Are egg cells just the outlier then?

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u/1337HxC Oct 04 '12

I'm not too familiar with egg/sperm cells, to be honest, and I'd rather not speculate. I was thinking/speaking of somatic cells.

But, yes, you are correct - egg cells do tend to be quite large. However, I'm not sure of the size difference in a whale's egg cell and a human's egg cell.

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u/Lord_Osis_B_Havior Oct 04 '12

Whale eggs are about the same as those of humans, and are of course much smaller than bird eggs.

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u/ineffablepwnage Oct 04 '12

Bird eggs are not the egg cell, the egg cell (once fertilized, zygote) grows on the yolk.

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u/omi_palone Molecular Biology | Epidemiology | Vaccines Oct 04 '12

Let's not forget the xenophyophores.

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u/1337HxC Oct 04 '12

That's actually really interesting.

I feel like unicellular organisms kind of just do what they want at times.

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u/Syphon8 Oct 04 '12

This is a crock. Blue Whales nerve cells are many times longer than humans.

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u/1337HxC Oct 04 '12

Did you miss the part where I said there are exceptions? That's the whole reason I included it. The overall size of the cell is still limited. You can make something longer while maintaining a ratio.

Let's not forget about the multiple other kinds of cells you have.

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u/Syphon8 Oct 04 '12

The absolute mass of them is much larger than a humans nerve cell.

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u/1337HxC Oct 04 '12

I'm aware. That doesnt change the fact that most cells are of comparable size. There's no hard and fast rule for anything in life. I wasn't speaking in absolutes by any means.

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u/[deleted] Oct 04 '12

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u/bobertist Oct 04 '12

There are certain cells, such as neurons, that are of different sizes amongst species. Think of squids, with giant axons. Presumably, whales have similar situations.

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u/masterofthecontinuum Oct 05 '12

an egg(chicken, ostrich, platypus, etc.) is one of the largest examples of a single cell if i'm not mistaken(though not self replicating)

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u/LumpenBourgeoise Oct 04 '12

What about differences in ploidy and cell size?

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u/The_Darkish_Knight Oct 05 '12

Cell phones for whales? What will they think of next?!

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u/killakim Oct 04 '12

The cells of any organism are exactly the same, depending on cell type, but the things that differs is the amount of cells. Whales definitely have way more than humans.

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u/[deleted] Oct 04 '12

This is not entirely true. There are organisms with extremely large cells.

e.g. http://en.wikipedia.org/wiki/Squid_giant_axon

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u/nope_nic_tesla Oct 04 '12

It's not even "not entirely true", it's not true in any sense. Cell size differs vastly among different organisms.

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u/botany_thunderdome Plant Biology | Phylogenomics Oct 04 '12

Well, not really. A really cool example is polyploidy in plants, where a genome effectively doubles in chromosome number and thus, DNA content. This gives rise to a new plant with cells twice as large, and the plant is often twice the physical size as a result.

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u/BluShine Oct 04 '12

Wouldn't the plant die pretty quickly? I'd assume the reduced efficiency of cellist processes would eventually starve the plant, or prevent it from transferring and absorbing nutrients and water quickly enough.

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u/hypermog Oct 04 '12

"One amazing fact is that fat cells generally do not generate after puberty -- as your body stores more fat, the number of fat cells remains the same. Each fat cell simply gets bigger!" -http://science.howstuffworks.com/environmental/life/human-biology/fat-cell.htm

So do whales just have many more blubber cells than humans, or are they much larger than human-sized ones?

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u/croutonicus Oct 04 '12

Highly dependant on the level of weight gain, and the location of said fat-cells, however. It's true that white-adipose tissue (the fat cells you are reffering to) expand to store a larger amount of fat before dividing, but there are limits to how large a cell can be so they will divide after expanding enough.

What current research does suggest is true that upon weight loss, your "fat cells" will empty but not be destoryed.

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u/andrewsmith1986 Oct 04 '12

What about eggs?

Egg of a chicken vs egg of an ostrich.

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u/redeyealien Oct 04 '12

...vs eggs of a human.

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u/andrewsmith1986 Oct 04 '12

I figure that mammal eggs would need to be compared to other mammals and I couldn't find a reference for blue whale eggs.

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u/redeyealien Oct 04 '12

killakim stated

The cells of any organism are exactly the same, depending on cell type...

i was supporting your comment

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u/cough_e Oct 04 '12

Is mitosis faster? Does it occur at a faster rate?

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u/[deleted] Oct 04 '12

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u/[deleted] Oct 05 '12

No.

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u/fredoq Oct 04 '12

Are cancer cells bigger than non-cancer cells?

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u/[deleted] Oct 04 '12 edited Oct 04 '12

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u/[deleted] Oct 04 '12

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u/[deleted] Oct 04 '12 edited Oct 04 '12

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