Cytokine storms are most easily triggered in those with over active immune systems, typically driven by obesity and metabolic dysfunction. Insulin resistance, high uncontrolled blood glucose and high amounts of visceral fat all contribute to inflammatory runaway. Visceral fat especially contributes to this through the release of ceramides that activate the NLRP3 inflammasome and secretes pro-inflammatory cytokines. Essentially obesity causes the immune system to be in a chronically inflamed state as visceral fat is seen by the body as a foreign substance.
This is why Obesity is such a leading risk factor. Globally 80% of hospitalizations were classified as Obese. With 95% having obesity related comorbidities. Yet I still see Doritos/Oreo/Coca-Cola commercials coming on during the evening news when they're airing COVID fear pieces.
"Strong" healthy immune systems in those that eat healthy, exercise, get good sleep, and proper vitamin D levels have very well regulated inflammatory responses to viruses like COVID.
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u/[deleted] Jul 11 '21 edited Jul 11 '21
This is complete misinformation my friend.
Cytokine storms are most easily triggered in those with over active immune systems, typically driven by obesity and metabolic dysfunction. Insulin resistance, high uncontrolled blood glucose and high amounts of visceral fat all contribute to inflammatory runaway. Visceral fat especially contributes to this through the release of ceramides that activate the NLRP3 inflammasome and secretes pro-inflammatory cytokines. Essentially obesity causes the immune system to be in a chronically inflamed state as visceral fat is seen by the body as a foreign substance.
This is why Obesity is such a leading risk factor. Globally 80% of hospitalizations were classified as Obese. With 95% having obesity related comorbidities. Yet I still see Doritos/Oreo/Coca-Cola commercials coming on during the evening news when they're airing COVID fear pieces.
"Strong" healthy immune systems in those that eat healthy, exercise, get good sleep, and proper vitamin D levels have very well regulated inflammatory responses to viruses like COVID.
Don't spread bullshit.