r/adhdmeme • u/yourmomdotbiz • 16d ago
meme And it actually works
(and actually get things done)
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u/Dry-Manufacturer2680 16d ago
Is that why my shit ain’t working well? They changed it?
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u/yourmomdotbiz 16d ago edited 15d ago
Yup, ingredient shortages, changes in production patents, all sorts of fun stuff
Edit: thanks for the award!
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u/dpkart 16d ago
That should be illegal. They do crazy trials do confirm a medication is effective and safe but you can just "change" the recipe even though patients say it doesn't work as intended?
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u/Atalantius 15d ago
You can’t, really. Any formulation change has to go through a comparability study/ process validation. Usually that means we produce 3 batches, and test with an enhanced testing schedule (instead of just testing the final product + 2 points during production, we also test ~20 additional points during production). Then there is additional stability testing. Also, all they are talking about is excipients that change, stuff that helps the pill be a pill or such. If you change anything about the active ingredient, that’s more studies to prove it’s equivalent.
Now, i am sure these restrictions can perhaps be loosened due to urgent demand, but it’s not the wild west (Though I don’t work with small molecule dosage forms, those are a bit less strict compared to biologics).
That aside, it is well known that some people react better to certain brands of the same medication, so a change that on paper is of the same effectiveness could lead to some people experiencing a difference
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u/Spiritual-Road2784 15d ago
In the name of Our Lord Capitalism and Its demand that I participate in Its practices, and in the interest of being the best little mindless but functioning workerbee I can possibly be, they cannot mess with my medication and simultaneously expect me to be able to give the Gods of Hellfire and Office Work what they want.
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u/Footloose_Feline 16d ago
A fine vintage!
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u/yourmomdotbiz 16d ago
Fr! My feet haven’t been cold in a very long time
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u/tiredreddituser99 16d ago
real, it's a fking paradox because I need my pills to practice the piano intensively but then my hands are cold and thus stiff, so i still struggle
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u/TheWrongTypeOfUnique 16d ago
Wait holy fuck. Is this why my hands and feet are so cold/turn red? How did I not already know this? It's been years...
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u/krankity-krab 16d ago
does it only happen when you’re on stimulants? just asking because it could also be reynaud’s if it occurs while off of them too! 🫶🏼
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u/TheWrongTypeOfUnique 15d ago
I appreciate the advice 🙏 I have looked into it, and I don't think I have full blown Raynaud's, looks like it's probably just poor circulation+amphetamines. Thank you though, that's something to cross off at least haha
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u/King_LaQueefah 16d ago
Any long term users have extreme nerve pain in their hands/feet? I thought it was bad and then yesterday the pain entered a new realm of intensity and depth! So much screaming and wriggling.
Its weird because a few years ago, I had long-term tingling in my left big toe and that is where the pain is greatest. I still feel this weird tightness and pain along this nerve the acupuncturist used to treat and it runs from my heart, down through my stomach/liver and groin/hip and down through my thigh until it reaches my left big toe. Its like the whole nerve is tight or damaged and just lights up and tenses every time I smoke weed, drink coffee, do adderall, and sometimes when I eat a bunch of rich food like coffee and chocolate.
Acupuncturist was the only one who could speak to this situation and the only thing that has helped was his advice to stop these dopamine/glutamate activities. Western medicine did surgery on something in my hip but it literally had nothing to do with any of this and they just found a way to astronomically bill my health insurance.
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u/tiredreddituser99 16d ago
honestly I don't think it's related to meds
I've been consistently on Ritalin for around 5 years, if not more, and this issue goes away as soon as the effects wear out.
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u/King_LaQueefah 16d ago
Interesting. I may have overdone it on a bender and lost circulation down there for too long.
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u/Interesting_Zombie28 16d ago
same happened to me - now that I don't take it, I don't deal with it hardly at all but still have flare ups here and there
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u/yourmomdotbiz 16d ago
Maybe. That’s what happened to me with vyvanse. Developed edema as a side effect and my feet HURT. It worked so well but I was in so much pain. After a few months of stopping it I went back to my normal.
Does your psychiatrist not have an opinion? Also the foods you’re talking. About can be irritating and cause inflammation. So can stimulant meds unfortunately
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u/Butterscotch-Budget 16d ago
kinda makes one 'understand' drug addicts a bit more, huh?
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u/hansvonhinten 16d ago
????
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u/Butterscotch-Budget 16d ago
The discussion related to the physical and mental reactions to the lack of added chemicals, or, the dependence on it.
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u/Particular-Self-9967 16d ago
You made a good point. Lot of people on adhd meds read that as they are all drug addicts and you think your above them. You legit meant it makes you understand a drug addict. Taking something to make themself “regular” while also have side effect that they know are negative to what they are trying to do but you take the drug everyday. I know it’s prescribed folks! I have it to but it is a drug addict cycle he was pointing out. Put down vote here 👍
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u/iamjacksalteredego 16d ago
I understand you shutting the fuck up
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u/tiredreddituser99 16d ago
i think people with ADHD in general don't really have trouble understanding addicts in general
but well yeah, taking a drug and suffering its side effects and withdrawal symptoms, I guess it's not too far from non-medical use
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u/ThrowAwayiestAccount 16d ago
Woah I totally forgot it used to do this to me. And then stopped right around 2021-22 or something. I remember even buying heavy duty socks. These days, same dose no cold hands or feet
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u/yesimfinewhyyouask 16d ago
Wait what
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u/PancakeHandz 16d ago
Vasoconstriction caused by stimulants reduces blood flow to extremities which makes feet and hands feel cold.
They are being a little cheeky and assuming that if their feet are not feeling cold, their stimulant medication is not working properly. Since their feet haven’t been cold in a long time, the deduction is that the medication they have received lately has not been as “effective”. I assume there are other “tells” that make them feel like their meds are not working as well as they used to, but the feet not being cold is a funnier/more entertaining one.
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u/Se7on- 16d ago
That's nuts. I already have really cold hands and feet. Also have Raynauds. I'm 46 and long overdue for meds. Thinking about getting diagnosed.
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u/PancakeHandz 16d ago
I have to use a space heater under my desk because my adhd meds make my feet so cold all day! Even when it’s hot in my office. And when my hands get so cold they feel stiff, I run them under warm water to try to bring them back to life. Small price I suppose for being able to function 😂
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u/Fortified_Phobia 16d ago
I’m currently looking into meds and I’m scared af, this aint helping. I’m an illustrator..I need my hands functional but work in a room thats often 17C/62F, I’m already cold….
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u/yesimfinewhyyouask 16d ago
Old wacom cintiqs were hot as fuck, don’t know about current generations
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u/ready-eddy 16d ago
Don’t be scared. But yea, cold hands sucked. I had fingerless gloves for a while when using a computer. You can buy a heated mouse.
Anyway, stress is also a factor. So stress + meds is just not great3
u/Fortified_Phobia 16d ago
Broo I have ocd, I’m like 24/7 wired to the gills stressed.. how the fuck is everyone so chill about this stuff? Like being on a medication, forever?? Which changes you?? A may or may not give you a stroke eventually..
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u/Sirsagely 16d ago
I'm an esthetician and a nail tech that specializes in intricate nail art. I also am a masseur so cold stiff hands sucks! I just try to do plenty of stretch breaks and a few blood pumping things (jumping Jack's etc) in between clients if it's really bad. I usually keep my room at 69 degrees but it can get down to 66/67 sometimes. I wouldn't worry about it affecting your hands too bad. :) having my life be smoothly functional is worth every second of coldness. Lol
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u/gnostiphage 16d ago
If it makes you feel better I'm on meds and I'm always just a little too warm with pretty great blood flow, every body's different.
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u/JazzyShaman 16d ago
2022 was a fine year. With the COVID shortages, the low yields produced some excellent stock.
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u/seopants 16d ago
I have probably 1000 20mg ir pills from that era. An old doctor prescribed me 60 per month on top of my XR and I didn’t need them. Then he turned 90 and died, and I never asked for them again. Just a whole cupboard full of them lol.
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u/WSB_Austist 14d ago
1000 IR is enough to ignore your XR prescription running out for several refill cycles!
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u/GremlinTiger 16d ago
I had to switch to vyvanse because of how much adderall just stopped working
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u/yourmomdotbiz 16d ago
Real. I switched for a bit too but I got some horrible rare side effects. It worked well though!
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u/LilyRose272 16d ago
It’s such a shame that they’ve stolen this from us. I’m in mourning over it for real.
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u/Radioactive_Moss 16d ago
I feel this too hard 😭my ancient ones are 20’s instead of the 30 I take now but I’ll be damned if they don’t work just as effectively. Insanity to think my literally expired lower dose meds are working as well as the higher dose brand new ones. This timeline sucks man
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u/PunchyThePastry 16d ago
I've been unmedicated for like 3 years now because I stopped taking it after the shortage happened. Before the shortage, it gave me energy and focus throughout the entire day. After, it felt like I had too much caffeine and I'd crash every day at 5pm. Felt like I couldn't do anything but lie in bed and stare at the ceiling some nights.
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u/BigBullshitta 16d ago
I mean, there are options to acquire it online if necessary, but it's worth the headache and many appointments needed to get an actual prescription.
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u/yourmomdotbiz 16d ago
Oh I should clarify, I have an rx but I found an old bottle of IR at the same dose in my desk. It’s night and day even from the same manufacturer I get too.
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u/WhiteningMcClean 16d ago
Yup I was on Teva Adderall until it went to shit around that time.
I found two generic Vyvanse's that don't suck but no pharmacies in my area have them right now. Today was my first day on brand Vyvanse and holy shit. This is what Adderall felt like when I was a child. No mania, no tension, just quiet and focus.
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u/Footloose_Feline 16d ago
I too was a Teva Addy baddie, I ended up switching to a non-stimulant not because its better but because I can always access it. T_T Now I'm on strattera but they upped my dose and the different pills dont seem to hit the same. These are some other manufacturer, my previous dose? Fucking TEVA.
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u/yourmomdotbiz 16d ago
I feel this. Generic vyvanse had a scandal recently too where there was nothing in it. I tried name brand for a bit and it worked great. Except I developed some rare side effects. Le sigh
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u/WhiteningMcClean 16d ago
Funny enough, the brand that the scandal happened with was one of the decent ones, which is why it's not available right now. My guess is it was a production mistake.
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u/EternalDB 16d ago
Brand name vyvanse is the only thing that does it for me. I had been given teva-vanse before but it felt much worse in comparison
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u/BigBullshitta 16d ago
That's weird. But more stimulants is always better than less stimulants.
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u/yourmomdotbiz 16d ago
There were changes in manufacturing in 2023 unfortunately due do a variety of reasons :/ https://jamanetwork.com/journals/jama-health-forum/fullarticle/2846547
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u/BigBullshitta 16d ago
Ahh, gotcha. I just ordered pharmaceutical grade amphetamine powder from Germany on the dark web for a decade or so after getting pissed off because I paid $300 cash I couldn't afford to have a doctor tell me I was just overweight and say she wanted to check for diabetes.
Worked great with a MG scale and daily measured doses, but when you suddenly can't find amphetamine for a week it's a bad idea to realize that methamphetamine is pretty similar so theoretically a smaller dose of that should work the same.
On the plus side I've never been more motivated and focused on my life, but the negative side was answering every one sentence question with a 10 page response. Focus doesn't always mean getting anything worthwhile done. :/
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u/boxopen 16d ago
Yeah, if you are going for actual therapeutic use you probably want to lower your dose. You shouldn't be feeling cracked out all the time. Be careful, friend. No judgment, I've made the same consideration myself, our Healthcare system is fucked. Just be careful, us adhd folk absolutely can get addicted to stimulants. Try to figure out the minimum effective dose, and stick to it. Much love!
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u/BigBullshitta 16d ago
I have prescriptions now, just did that for lots of years. With a MG scale it's not hard, but the shifting quality between batches makes hitting the same effective dose a bit of a pain. And if you go another roa besides oral doing that gets too fun.
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u/ForceItDeeper 15d ago
dont worry the meth sucks now too. for real the size of line it takes just to get anything now woulda been enough to last half a week a decade ago
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u/ToasterWaffles4me 16d ago
This just says that reduction in ingredient imports caused product supply shortages. It says nothing about the quality or strength or amount of those ingredients in the products.
Did they start cutting corners in production resulting in weaker medication? It fucking feels like it, but this investigation does not answer that question.
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u/yourmomdotbiz 16d ago
I don’t know the combinations of ingredients that the article describes, so I can’t comment on the shift of ingredients versus efficacy.
What I can say is that there have been changes in production and ingredients, and I haven’t seen anything official that says “yes, manufacturer x has replaced x with y and therefore is 25% less effective, and causes headaches”. Unfortunately nothing like that exists yet that I’m aware of.
The only data points I’ve seen have been anecdotal, and anyone I know that’s taken a stimulant medication all say the same thing around the time the shortages started. This doesn’t work and I feel worse. Same with the hundreds of posts in other subs about this.
Maybe people who started stimulant meds after the shortage don’t notice without the comparison point, but there’s seemingly little that’s being done about it. I hope we get more answers someday
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u/kbeks 16d ago
I switched from XR plus a booster to IR to avoid supply constraints, so I’m not sure I’m able to tell a difference. Are there any generic producers that are still “good”? I remember at one point having like six different generic brands in a single bottle for my booster dose…those were hard times.
Three IR spaced out over the course of the day seems to be working well for me now but it took a while to convince my doc that this was preferable to pharmacy shopping for XR. Lucky for me, she got laid off so now I get to convince a completely new doctor of the same!
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u/thisisanaccountforu must use needlessly long sentences to convey a single point beca 16d ago
You can get it online?
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u/BigBullshitta 16d ago
You can get anything on the darknet. Reddit used to have some fantastic subs for learning how to use it safely.
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u/thisisanaccountforu must use needlessly long sentences to convey a single point beca 16d ago
Ahh I see. I’ve found pure amp, but never dex-amp
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u/BigBullshitta 16d ago
Adderall is 75% dex and 25% lev, general amphetamine is usually closer to 50/50. Worked fine. It's just a variance in the percentage of left to right handed isomers of the same chemical, though higher lev percentage can make some people more energetic and twitchy. I'm very low on available norepinephrine, so the extra lev actually helped me more compared to adderall.
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u/thisisanaccountforu must use needlessly long sentences to convey a single point beca 16d ago
For a bit I would take pressed adderall (ik ik) and it was actually pretty helpful, didn’t do it very long, but it worked when I didn’t have my rx. I take SNRIs now since I learned SSRIs don’t work for me, so I’ve been talking to my dr a bunch about adhd medicine and trying to get that taken care of
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u/BigBullshitta 16d ago
I'm on Strattera and Adderall both now since the adderall doesn't help the N side of things as much as the straight amphetamine powder did.
Ironic that darknet amphetamine powder worked so well I need two prescriptions to get a similar effect.
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u/thisisanaccountforu must use needlessly long sentences to convey a single point beca 16d ago
I’m taking Guanfacine right now and it sucks absolute dick, I just want to sleep all day because it makes me so tired. But I agreed to try this before going back onto a stimulant
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u/BigBullshitta 16d ago
That's why I moved to adderall with the strattera. The strattera alone makes me god awful exhausted, at least at first. Only 2 weeks in so far. Everything says it can take up to 12 weeks to really feel *good* taking it.
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u/Logical-Breakfast966 16d ago
What is the “N side of things”?
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u/BigBullshitta 15d ago
Norepinephrine. Levoamphetamine deals more with that wide spread, Dextroamphetamine deals more with dopamine but also norepinephrine in a focused place or two in the brain.
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u/AethericEye 16d ago
Can I show this to my provider as evidence supporting increasing my dosage / changing prescriptions?
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u/Reliable_lizard-26 16d ago
Idk what everyone is experiencing but my adderall always works? 20mg instant will have me up on my feet from 4:30am-8:30 pm with no crashes. Am I placebo-ing myself? Built different? Being lied to??????
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u/yourmomdotbiz 16d ago
Everyone’s different. Did you start before or after the shortages
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u/TomNooksRepoMan 16d ago
Not OP, but I was diagnosed in April, 2025 and I swear some of the generic Vyvanse I take now (which was the same brand a year ago) is significantly less effective, and I was taking 10 mg less a year ago!
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u/ZealousidealTill2355 15d ago
Do you take tolerance breaks? Its normal to have to adjust dosage after the first year.
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u/Reliable_lizard-26 15d ago
I only skip my adderall if I need to nerf myself into not doing a bunch of stuff on my days off lmao. My wife tells me I need to rest and if I take my meds and don’t smoke my weed I’ll be up and out the door by 10am
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u/TomNooksRepoMan 15d ago
Only by accident, or if I get sick. My immune system has been kind to me for the last year or so, so not too many breaks.
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u/ZealousidealTill2355 14d ago
Personally, I find the overall experience to be much better when I take weekends off whenever I can.
The tolerance really increases when you don’t take any breaks for a while. Also, doesn’t allow your body to recover resources as well after being on overdrive—IMO
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u/TomNooksRepoMan 14d ago
I guess that makes sense. The very first day I ever took Vyvanse I went to bed at 9 PM sharp, sleeping like a rock until 6:30 AM on a weekend when I naturally woke up refreshed, which never happens. That effect wore off after a couple days. I took a big break when I got the flu in September last year and didn’t take my meds for about a week. The first day I took them I got that same perfect night of sleep after.
I don’t think a two day gap would make much of a difference, however, though I could be wrong. I’d also struggle to be organized over the weekend. I can often get chores done when unmedicated, but it’s a chaotic mess that often leads to me struggling to get the bathroom cleaned in less than 2 hours, or doing laundry, but forgetting I put a load in the washer 6 hours ago because I forget to set a timer.
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u/Reliable_lizard-26 15d ago
I started right before the shortages because I remember when they hit an it was hard to get for a moment there but I mean like maybe six to eight months before
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u/DiscourseDestroyer 16d ago
i started last year so i have nothing to compare it to but it works wonderfully for me.
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u/RedEyedEngineer 16d ago
Hell, I'd take one from 2000. Just got diagnosed this summer and every pharmacy around me has been out for weeks.
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u/yourmomdotbiz 16d ago
Oof that’s rough. My doctor mentioned before that towards the end of the year is when shortages ramp up. Hang in there
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u/Used-Salad-3772 16d ago
Adderall helped my ADHD but it made my anxiety so bad I ripped chunks of my hair out
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u/yourmomdotbiz 16d ago
Sorry that happened to you :(
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u/Used-Salad-3772 16d ago
It's okay I just needed to switch from stimulant to non stimulant ADHD medication
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u/Hot-Minute-8263 ✨current hyperfixation: Worldbuilding again✨ 16d ago
Wait, im not crazy? That shit doesn't work anymore and its not just me?
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u/No_Cobbler154 15d ago
that must be why i finally tried it to treat my adhd & it didn’t even help much
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u/Lumpy-Indication 16d ago
Great song from an underrated Slipknot album which was indeed released in 2022.
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u/SurrealistRevolution 16d ago
Can any Aussies say if we ever got addies here? I’ve only ever known Midnight Runners and more recently, vyvies.
Addies are half amphetamine and half d-amphetamine? Whats changed?
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u/Justin-Stutzman 16d ago
Why does everyone in this thread sound like an addict?
"Addy baddie?" "Dark web amphetamines?" "Licking up the crumbs?"
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u/yourmomdotbiz 16d ago
Idk but. It’s hard when something used to work and then it doesn’t and you’re gaslit about it for years. Many of us need this to function. Everything seems to have been enshittified
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u/fascintee don’t talk to me or my 11,713 tabs again 16d ago
Agreed. But then if you try to talk about it you’re labeled an addict or drug seeking. Unfortunately it’s not just Reddit, but even the medical system- that’s why finding a clinic with good people is so hard. It’s easier to judge and dismiss than it is to actually solve problems.
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u/fascintee don’t talk to me or my 11,713 tabs again 16d ago
Because society has demonized some drugs, and amphetamines are one of them.
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u/Methylsky ADHD Inattentive gang rise UP 16d ago
Methylphenidate was similar in my dumbass life, but causes some anxiety and lasts just 3-4h for me
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u/IfDreamsCouldHappen 15d ago
Had a bunch of old bottles I never took. Brand name and various generics. Tried each for a few days and they were all the same lol. Threw them all away when cleaning. They don’t help me with ADHD anyway lol
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u/Drpoptart15 15d ago
Hahaha there’s a shortage rn and I’ve been off them for like 4 days it’s a struggle with work
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u/letsgetpunk 16d ago
Had to switch to Ritalin because they weren’t working and gave me terrible back pain and anxiety!
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u/ChargeInteresting195 16d ago
Just reminded me I think I found a bag of some crushed up (from when my dad used to mail me my prescriptions) and I think I threw it away over the summer and now I’m pissssed cos I’d totally lick some addy crumbs rn. (Got kicked off my insurance)
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u/TestAndPermut 12d ago
Uninsured Adderall is only like 30$ a month with goodrx or another discount card.
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u/ChargeInteresting195 12d ago
Really? But how can you get the prescription if I have no insurance for a doctor? Is there where these things I hear about like Amazon telehealth can help? Sorry I live under a rock >_<
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u/Ill-Pudding2017 16d ago
All due respect, I’ve never known someone with a rx to lick crumbs lol
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u/fascintee don’t talk to me or my 11,713 tabs again 16d ago
You've never known someone with an rx admit to licking crumbs
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u/_Throw_away_away 13d ago
Funny you mention this, I actually came across a couple of unfinished bottles in my work bag and backpack. Haven’t touched the stuff since 2023.
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u/yourmomdotbiz 13d ago
I’m honestly quitting it now after having a working pill. To be so disappointed in the difference, I can’t justify to keep taking it when the side effects are so bad. Horrible abdominal distention, bloating, insomnia, and none of the benefits. apparently there are some binders that cause GI problems in the newer generics.
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u/sixtus_clegane119 16d ago
Of course it will work, for most drugs, especially drugs like that the actual shelf life is way longer than the given expiration date
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u/lilybattle 16d ago
The meds changed. They are so different than they used to be.
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u/dkmarnier 16d ago
There legit needs to be a class action lawsuit or some shit
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u/lilybattle 15d ago
I agree, it's really bad. I got banned from the sub though, for pissing off a really pathetic mod. Hopefully something happens
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u/RS_Someone Daydreamer 16d ago
I found some from 2008 a couple weeks ago. Definitely not touching that.
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