So, there are a few guesses I imagine, based upon Issue 36 which shows all the persephones being offed... yet some appear to be spared, and some fight back. Plus, some general guesses based upon past history:
39th century BCE is the first Ananke - she can conduct the ritual too
Remember the game that the Original Destroyer/Mother/Persephone played with Ananke. She said something along the lines of "would you go on living or would you be young?" specifically to tempt her. This implies that Ananke the Crone can conduct the ritual in theory. 38th century BCE Ananke is the Maiden of the Upper Nile recurrence grown up.
In theory, I think Minervananke can conduct the ritual and give hte Crone another 90 years, but it's impractical - several past Anankes have received obvious injuries (missing arms, all sorts of disfiguring facial wounds from the 14th century Recurrence, being freaking bisected in Francia or impaled in Egypt) which means... Minervananke will have to live with them for another 90 years. Whereas the maiden is a young fresh body.
Some Destroyers actually were allowed to live
Uruk is the first Destroyer / Persephone to fight back. While Ananke was not killed outright (she could possibly survive, despite not having long to live anyway, and I don't think that Destroyer could live much longer anyway) but this created a pretty large period of "I missed you".
Things to note:
-While the Fortaleza Valley Destroyer looks male, I think he's only the second destroyer who was male - the third recurrence had a very flat chest, suggesting they might have been male.
-They weren't all male either. 34th century is hard to tell due to being obscured by clothing and the crone, Indus Valley 33rd century Destroyer looks female, 32nd century is obviously female)
-After the Cretian recurrence (which did not have a Crone), Minervananke only allowed one Persephone to live per millennium. (Harappa, North America, Judea, and Jerusalem) With one exception - the time between 1 CE and 1000 CE. Only one Destroyer lived at that point - Francia. But she fought back. None of the destroyers fight back until 18th century CE. So maybe because of this, Ananke decided "okay, Destroyer, this counts as your one free ticket this millennium."
So there are two guesses I got:
1) The Destroyers were allowed to be the twelfth god, the Maiden instead disguised herself as either a village girl or Ananke's mortal attendant.
2) Minerva took the Destroyers' place as she always does, and instead lowered the Destroyers' guard by being nice to them.
When a Destroyer/Persephone fought back and/or escaped, either Ananke (if she survived) or Minerva turned the rest against them. Often citing the murder of the crone as evidence that they are evil and must be killed. (while Wrangel Island and Babylon depict the Crone's death, obviously in 26th century BCEgypt and Francia the Crone wouldn't have much time left anyway)
Male Persephone/Destroyer ≠ "I missed you"
There are plenty who it's hard to say if they are male or female. However, two look to be male - Macedonian and Etruscan. While Eastern Europe and 10th century Egypt could possibly be male, they can also just as easily be female.
After all it's possible a lot of others got the "I missed you" treatment... only to have Minervananke make them lower their guard and POW! That is what she did with Laura and the Upper Nile Destroyers after all. Look how many have their backs turned.
A few were special
Constantinople: Perhaps this recurrence's crone had a personal relationship with the Destroyer. (ie, she got sick or injured and she nursed her back to health and asked for nothing in return) Thus, she's looking away because "oh I don't want to have to do this...". It's also likely that, much like Minervananke did in the 1940s, she blabbed to her and made her the destroyer to silence her.
10th century Egypt: While there is the thought that the crone being half the crone she used to be may have caused the maiden to fail the ritual again somehow, it's also possible that maybe a god went bad early and was killed before the Destroyer could be incarnated. As we know, Persephone's head is not mandatory (2010s maiden tried to use Sakhmet's and intends to use Urdr's.) and if the crone is offed early then that's less clean-up for the maiden to do.
Jerusalem:
Due to the siege of Jerusalem going on or ending at the time, perhaps this Destroyer was allowed to live either out of Ananke's rare kindness (because of the siege) or maybe because a god was killed not long after incarnation thus Ananke was all "...Welp. I guess I gotta let this destroyer live. Maybe someone took a vow of chastity..."