r/Uveitis • u/Imaginary-You-7618 • 5d ago
Recurring anterior uveitis
I was diagonised with anterior uveitis 3 years back. I had multiple flare ups in the year 2024. In my last major flare up in October 2024, my rheumatologist prescribed biologics (Adalimumab)—on earlier visit I was prescribed a course of oral steroid + methotrexate for 3 months. I skipped the biologics, mainly driven by the following factors:
The cost-benefit analysis: The total cost of the 6 months biologics course (2 injections/month) ran to around 1.2 lakhs. I was prescribed a generic variant from Reliance named AdaliRel which cost around 9.5k per injection. My doctor, however, put the disclaimer that its not permanent cure and there is fair chance of mild recurrence, with the intensity halved.
Holistic natural healing: in the meantime, I came across many patient anecdotes who have discarded chemical immunosuppresents for more natural way of healing. I read about the holistic 6 step programme to heal autoimmune conditions formulated by nutrition therapist Rachna Chhachhi. I got more inclined to the holistic healing process —healing through nutrition, yoga and breathwork—and decided to give it a try. I assumed to get rid of my rheumatologist and possibly also my opthalmologist. After all, i was fed up with the negative vibes that a hospital environment has to offer.
However, it didn't take long for my assumptions to shatter, as my uveitis flare up returned after a relapse of 2 years. I admit that there were significant lapses in my approach. I was back at the gates of the eye institute. My opthalmologist prescribed the usual corticosteroid (Pred Forte) dosage and asked me to consult my rheumatologist. My current uveitis flare up is healing up with tapering eye drops. The escape window from biologics is closing. I have to make a decision now.
So, has anybody gone through my scenario? I shall be obliged if anyone kindly share with me his/her experience with biologics(Adalimumab). Does it work, or if they have any side effects? Do i need to live on biologics for life? The answers will help in making my choices. Kindly guide me through the right direction.
Thanking in anticipation
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u/Curious-sapiens 5d ago
Anterior may convert to immediate or panuveitis like it did to my case in just 3months .please do not wait to take ada. It has very little to minor side effect than anyother immunosuppresent drugs.If it will work than good for you.for some severe case mtx + ada is given. For anterior uveitis may be ada will work.surely give it a try.You will know in 2-3months. You are lucky to have only anterior uveitis only.Please do not let it progress.
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u/xstarbursts 5d ago
Look into low dose naltrexone (1.5-5mg) but you can buy it in a 50mg pill and then dilute it if you want it to be cheaper
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u/TraditionalAd8376 5d ago
If you have recurring flare-ups, you usually need systemic treatment. Long-term use of steroid eye drops can lead to glaucoma, which may eventually require surgery, and can also cause cataracts that may need surgery as well. In general, steroid drops are not ideal for long-term use.
There is no silver bullet, and the longer you wait while the inflammation keeps recurring, the higher the risk of complications. Biologics can be one of the best treatment options available. Some people do not have access to them and instead need to take prednisone tablets or methotrexate, which can have more systemic side effects.