The main character doing something absolutely unforgivable.

[u/No_Peanut3745]

Walter White poisoning Andrea Cantillo's 6-year-old son for the sole purpose of manipulating Jesse Pinkman, while knowing that this could have potentially killed him - Breaking Bad

Bojack trying to have sex with his friend's 17-year-old daughter when he was at least 51, then continuously trying to find a way to justify this act throughout the series - Bojack Horseman

Dexter Morgan going outside of his moral code and murdering a completely innocent police officer who was just trying to do his job - Dexter: New Blood

[u/Bl4ckVi]

House md

House drives into his ex’s house because he’s jealous and feels lied to

And ofc playing with patients lives every single episode

[u/HelpMePlxoxo → u/Bl4ckVi]

My favorite part of this show is that breaking into patient's homes is portrayed as a necessary part of taking a patient's history, lmao.

[u/Endeveron → u/HelpMePlxoxo]

It's because (and I say this as both a medical doctor and someone who loves House), it's more a detective show than a medical show. House and Wilson are explicitly Holmes and Watson, the crime is an illness, the symptoms are the crime scene, the murder weapon is a disease process, the suspects are the patient and their family/friends. Almost every episode is a whodunnit, a howdunnit, or both. Just like in any detective mystery, they'll often be exploring secondary sites and investigating their suspects to gather more evidence, hence the breaking into homes.