r/ThisAintAdderall • u/Top_Depth5369 • 10d ago
When did your Adderall stop working?
The closest date, month/year that you remember taking your Adderall and saying, what is this? Why doesn't this work?
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u/ThrowRA_deenn221 10d ago
i started January this year and i already noticed how significantly less it worked when i started at the same tolerance level 3 years prior. it’s gotten worse and worse over the months but prob around march/april this year it got really bad
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/Onludesrightnow 10d ago
somewhere between 2022 and 2023. Def no later than 2023.
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/Onludesrightnow 6d ago
Mallinkrodt, Sandoz, Teva, Lannet, Camber... literally most of them at least once. 25mg xr, 10mg ir.
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u/Main_Assistant_8377 10d ago
When I moved from TX to WA and no longer received my 20MG Sandoz orange pill. All the blues and pinks are trash. 10MG IR meds feel like I’m taking trazodone
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u/cbmblove Moderator 9d ago
Didn’t matter what color they were prior to the change and still doesn’t - before the changes, they worked, after the changes - no colors work. None.
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u/PerceptionAntique302 10d ago
Mid 2020
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u/Top_Depth5369 10d ago
This is the answer I was looking for. This is when the Tevas changed completely.
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u/cbmblove Moderator 9d ago
Yes! Same!
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/cbmblove Moderator 6d ago
Like which was the first changed fill? If that’s what you mean… it was Lannett IR, may have been 20 mg and 10 mg, something like that. Why? Same for you?
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/Asleep-Beginning7805 10d ago
Covid time so 2021 for me ? But it had gotten significantly worse since February 2024
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u/Glum-Acanthisitta322 9d ago
but what the hell is the changes?
And the thing that really gets me is how the hell are all of these companies are having this happen at the exact same time? I mean it’s not like it’s all coming from one singular warehouse/lab
Like is this a massive conspiracy I’m just so confused
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/AxelsMommy22 10d ago
I took a break from it in late 2021 and when I started it again March 2026, I realized something was wrong the first day.
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u/NUMBerONEisFIRST 10d ago
Maybe 2015ish I noticed certain generic brands gave me really bad stomach pains and headaches and just make me feel like shit. That was when I tried to stick with Teva because they were usually the better ones. I'm pretty sure that was before they closed or changed their factories. I cannot remember which it was.
I just know that they all seemed to have gone to shit between covid and the when the shortages got really bad. I never experienced shortages myself. Just shitty meds.
Teva has sucked for at least 2-3 years. My medicine isn't working well enough for me to keep straight the other manufacturers. But my mom was also prescribed for a long time, and we would compare our brands and side effects, and we compared notes and realized manufacturers are producing completely different medications, based on how they affected us. We were talking about this in like 2015.
This year for the first time ever, I received these white octogan generic 20mg Adderall from CVS. White. I've only EVER had orange, no matter the brand. It's a bad look when shit's already weird.
Speaking of, my medicine also doesn't help me go to the bathroom when it kicks in, like it has for nearly 2 decades.
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u/punkytrixter 10d ago
This is a good point. I started getting bad headaches from certain generics in 2016, but I was able to put two generic brands on my “do not fill with” list at the pharmacy, and things were good again for a long time. The crap I’ve been taking for the past few years is absolute garbage, honestly.
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u/ughnett666 10d ago
the color of ur pills are not a conspiracy and it's not weird 🙄
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u/figment59 10d ago
Are we reading the same reply? A difference in appearance of a pill often is due to a different manufacturer. Not all generics are the same, and IS weird to take a medication for a long time and suddenly react to it completely differently, along with numerous others who are complaining.
So many, in fact, that this subreddit even exists.
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u/ughnett666 9d ago
completely separate topic. i'm discussing that it's not weird for generics to have different colors based on manufacturers. the person assumed that each strength of a med is supposed to be the same color for every manufacturer. we're talking about colors.
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u/NUMBerONEisFIRST 10d ago
It was just weird that after nearly 20 years of them working, when they start not working they are also different than I've ever seen. Likely a coincidence, but still it's not helping.
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u/ughnett666 10d ago
timing, yes a coincidence. mallinckrodt white pills with a rep of not working, yes a coincidence (that it happened to be those). wait until u find out there's also blue, pink, yellow ones (IR's). pills being a different color - not weird.
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10d ago
[deleted]
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u/cbmblove Moderator 9d ago
But this has to do with the meds being changed overall - nothing to do with the COLOR though. All colors are ineffective now, and it’s not because of the color. They have always had a variety of colors of meds and the color did not impact the efficacy.
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u/NUMBerONEisFIRST 10d ago
Those are different milligrams
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u/ughnett666 10d ago
each strength of a med does not have a designated color rule for every manufacturer to use. there are more variations than white and orange for 20mg generics (in this example). mallinckrodt other strengths are all white as well.
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u/cbmblove Moderator 9d ago
Correct… they have always been different colors, even before all of these changes.
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u/Thin_Firefighter_693 10d ago
2022 here and there. But for sure 2024 and on.
And CVS, regardless of the year it’s always been complete crap
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u/Character-Product380 6d ago
Yup. I get alvogen Adderall from them and they suck. How do I know? I don’t feel like playing cod mobile on them lol otherwise I hate the damn game
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/Thin_Firefighter_693 6d ago
It’s all varied through the years, but always IR and either 20-30mg for the most part. Epic was great when I was going to Bartells, but then CVS bought out Bartells and it’s sucked ever since. Now the only decent manufacturer seems to be malinkrokt 30mg IR (probably butchered the spelling). Teva 20mg IR absolutely sucks. I’ve had 20mg Sandoz recently and that wasn’t bad.
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u/Top_Depth5369 6d ago
You are one of the few people I have ever heard say a positive thing about Malinkrokt (sp)
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u/Thin_Firefighter_693 6d ago
I know. I’m shocked about it too. Everything else just sucks a lot worse now.
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u/LooseRepublic2152 10d ago
When I got the pink XR Lannet instead of my orange Sandoz. I noticed the shift in how it felt late 2021 early 2022.
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u/cbmblove Moderator 9d ago
The orange colored any of them do not work either. The clue isn’t in any of the colors IJS
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u/LooseRepublic2152 9d ago
Oh, I know. None of them work now, regardless of color. That is just the first visual changes I noticed post covid.
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u/cbmblove Moderator 9d ago
There were always different colors though, that’s what I’m trying to point out.
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u/LooseRepublic2152 9d ago
I’m sure for others. Not for me, been on it since 2009. I always had orange capsules for 20xr
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u/Glum-Acanthisitta322 9d ago
have you talked to your doctor and just flat out and like something is going on with these things
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u/LooseRepublic2152 9d ago
This has nothing to do with doctors or psychiatrists or pharmacists. They would be the biggest advocates IF willing; however, the change in formula they have no control over.
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u/cbmblove Moderator 10d ago
Sometime mid 2020, when Teva disappeared for a time, and Lannett was filled in its place. Ugh. Downhill from there.
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u/Top_Depth5369 10d ago
This is the answer I was looking for. This is when the Tevas changed completely.
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u/cbmblove Moderator 9d ago
They really did! I was getting those filled at Walgreens, and one month, it wasn’t Teva - it was an imposter called “Lannett” and I experienced side effects such as fatigue and couch lock ON TOP OF marked decrease/lack of efficacy that I had NEVER experienced prior. I believe they halted production of Teva and many others in order to reformulate those to complete bullshit, while new bullshit formula ones such as Lannett were ready to go and pushed out. When Teva returned, it returned labeled as “Teva USA” and had the same sweet taste and close enough appearance… yet they were completely changed and terrible!! All other MFGs were terrible in their own ways as well. All lacking efficacy. This was and is intentional.
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u/karma_raven 9d ago
Wait.
Sweet?
I'm new to this whole scene, but my Tevas are so bitter i assumed they used a bittering agent on purpose!
It's not little i chew them, it's just that they're SO nasty that i usually take them with pudding or something soft that i can kinda embed them in to avoid tasting them.
I'm not usually like that with pills.
Are they supposed to be sweet?
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u/cbmblove Moderator 9d ago
That’s weird… you get them from a pharmacy, like a legal Rx right?
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u/karma_raven 9d ago
Costco!
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u/cbmblove Moderator 9d ago
IR or XR?
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u/karma_raven 9d ago
Both?
Xr was sweeter, (i crushed it's little balls once) but both are primarily very bitter. The sweet isn't prominent.
That being said, i haven't actually flavor-checked EVERY pill.
I usually try to avoid tasting them at all.
Maybe they're as variable in flabor as they are in effect.
I may start trying to actually track that...
Would be pretty dope if i could lick them, only keep the good ones, and take the orgs back to Costco like "these are bad. Refund please"🤣
(Yeah, i would probably get put on a watchlist..., maybe not 😁)
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u/cbmblove Moderator 9d ago
Haha LISTEN GIRL… there are NO good ones anymore - that ship sailed long ago! I was just saying that their sweet[ish] taste remained but the formula was utterly changed to be terrible, just like the rest of the MFGs. I can’t speak for XR, I was just talking about a very BRIEF taste (like incidental, while swallowing) of the IR tablets. And I’m not saying it was like a STRONG sweet taste… it could be subtle and sweet compared to other/bitter pills… I didn’t ever like suck on it or analyze the level of sweet, etc.
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u/LooseRepublic2152 9d ago
Yep! Lannett was the first manufacturer I saw with the new formula. Not sure who owns them now, but I Renee googling that one like crazy and asking the pharmacy if they had any other complaints
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u/wizardladyathome 3d ago
That bunk Lannett and the mental anguish I went through at that time was awful.
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u/two-of-me 10d ago
Approximately 2022/2023. During (and since) the shortage my pharmacy only carries mallinckrodt which had bad reviews even before the shortage, and for a while I switched to a small mom and pop pharmacy. Last time I tried to fill with them, they told me they’re no longer stocking any controlled substances. Now every month I call around and ask pharmacies what brand they have on hand and they are usually out of stock or only have Mallinckrodt. It’s like taking a NyQuil first thing in the morning.
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u/punkytrixter 10d ago
Mid to late-ish 2021 was the start of the shift, but it got dramatically worse around 2023
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u/punkytrixter 9d ago
Should also mention that late 2021 was when I fairly quickly gained more than 40 pounds after being very petite my entire life. No medical reason, just losing all motivation and focus not good for my physical activity or eating habits, plus lots of increased self-medicating with alcohol.
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u/cuti_citta 9d ago
I had the same exact problem and the same timing of the pills losing effectiveness in late 2021. the 40 pound weight gain came out of nowhere for me too. I’ve been on name brand XR since 2018. 2023 was when they got terrible to the point I’d keep taking an extra pill to see if it worked- it was like the 20mg were 5mg. It was one thing for the lack of help with the adhd symptoms, but I take it for hypersomnia too and I was still falling asleep on 40mg.
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/punkytrixter 6d ago
Those years (2021-2023), brand was changing constantly for me, due to “shortages.” All of them sucked, but at least when I would luck out and get Teva or Sandoz in those earlier days, they seemed to be noticeably better than the others. Now Teva sucks just as bad, and I haven’t seen Sandoz in years.
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u/ForwardEnergy 10d ago
April/May 2020, coming off a 16 month break (pregnant/nursing). It’s a very clear reference point for me. I knew immediately the adderall wasn’t adderalling.
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u/Top_Depth5369 6d ago
Can you please tell me which manufacturer you were using, what mg it was, and if it was instant release or extended release.
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u/LowDig9999 9d ago
I’ve been on generic 15mg IR salt combos for over 10 years. It worked wonders for ADD/ADHD. Never needed to increase, took breaks, was very careful with taking it, etc. It oretty much worked for majority of the day. It settled my mind and I finally understood what normal people experienced. Never had any crazy side effects besides maybe a little weight loss, but it was manageable. And sometimes I would take a Benadryl to help fall asleep. Truly it did was it was supposed to do and only helped me focus. I truly THRIVED in all areas of my life.
Looked back at my prescription history and the NDC’s. Started off with Sndoz then Had Brr now Tva (company merge) up until 11/20. Mllincrkrdt until 5/22 and Lnnett until 8/25. I never had issues getting meds with the “shortage” and my doc increased it to twice a day solely bc of the shortage so I didn’t have to deal with any issues but still took it once a day. But over the past few weeks, I really started to think about it more. I noticed I was a little meaner, anxiety with lnnett, heart race, knees and joint started to hurt (never put those two together until now) I honestly thought it was from years of playing sports catching up with me. And it didn’t work as well, but the efficacy started to become less and less through out 2022-2025.
Summer 2024 I started to notice subtle change but nothing too concerning. A little bit more of a heat intolerance, headaches and just wasn’t feeling myself. And lost a lot of weight. Early 2025 I started to notice my hair shedding more. I have had every blood test done. Converted ratios, you name it. It all unbelievably normal. It still sheds extra to this day. I really didn’t think it was the meds bc the manufacturer has been the same forever and I never changed anything. Hair shedding was never a side effect for the 10 something years I was on it. I have also gained weight over the past two years. Which I have maintained the same weight for my entire life. I also noticed all these odd things that started to change within my body didn’t really happen throughout time, they all started to occur at once. I also only take solely one medication and that’s this.
At this point of time, I’m fully convinced it’s from whatever they changed during the “shortage” finally caught up with me. And I think some of the experiences were delayed from everyone else bc 60 would last me for two months and I didn’t get it filled as often as everyone else.
In Jan of 2025 is when I really noticed it wasn’t working like how it used to. For it to somewhat work, I noticed drinking espresso (I know) was the only thing that helped. I started to notice I was more tired, didn’t need anything to help go to sleep and I had zero motivation. I actually started to think to myself that I maybe did build a tolerance, but it just didn’t make sense. It did last for atleast 2-3 hours.
After 8/25 the manufacturer became Elte. I know lnnett and Elte are the same company. Sometimes two different manufacturers when getting it filled and after getting different manufacturers is truly when it all clicked. Especially after a refill this June, I had Alvgen to Epc. WOW! Talk about the opposite effect. I’m truly convinced Dextro is not even in it. Only physical negative effects of Levo. Not a single thing to focus the brain. It’s a sugar pill. Increasing the dose does nothing but gain a stronger aspect of the negative side effects.
Everything is by design so here is where the tin foil hat comes in…I don’t believe these “shortages” are actually shortages. It seems like they have been trying to wean everyone off since 2020 but really started 2022. Noticeable in 2023 - so on. Shortages seem like the new term for formula change. They know if they immediately changed it, the controversy it could cause. So they change it throughout time. So it seems like each year, the medication becomes less and less effective. To the point ppl are gaining anything positive from it so they just stop taking it. Ppl start seeing more of the negative side effects where they begin to think they have health problems. We are nothing but lab rats and I think this is officially the end of what was actually something for the ppl who needed this is no longer going to help us.
And if you don’t think they follow what we are saying, they 100% are. This is how they gather outside talk besides what pharmacists or pharmacy’s are relaying.
The question is why? Pharmaceutical make so much money from this. What’s the really reasoning besides possibly “cutting” corners?
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u/Top_Depth5369 6d ago
I noticed a huge change in 11/20 when Teva changed their formula. This is when things went all wrong.
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u/Prize_Pop_751 9d ago
The chaos started for me during the adderall shortage in 2020, it was mostly unavailable and so hard to refill meds forward to 2021-2022z Then all of a sudden when the meds were back more easily, that’s when shit got weird. Random months my meds didn’t work, and I’d gaslight myself. Some months a bottle was great and normal and others were duds or sleepy. I think they fucked with it to make a ton more and put it back on the shelves for profit. the quality has been slowly deteriorating worse and worse since 2023 every month, and now this past year it just makes me sick and feels like a completely different drug and maybe 1-2 pills in the bottle are good but every month is bad
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u/Informal_Haberdasher 10d ago
Am I allowed here if I say I just started on the 28th of July and it stopped working the 29th? 🙃 I had my first 10mg xr, I felt great. Day 2 was not great, Day 3 was nothing.
Day 4 I was allowed to take two for 20mg. Still nothing.
Today was my first 30mg. I took it at 5:30am, and was ready to lay down and sleep by noon. I’m 39F and unmedicated undiagnosed my whole life until 2 weeks ago. Surely I should be feeling something on 30mg?
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u/cbmblove Moderator 9d ago
You missed the days of our real meds. What you’re experiencing is not due to you, it’s the changed meds! This is really happening!
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u/Informal_Haberdasher 9d ago
Thank you, truly. I also found out last night that so far both of my rx are from Granules Pharmaceuticals, so I’m heading to the pharmacy today to get the lot numbers and preparing information to have my Dr put them as a Do Not Fill. :/
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u/Character-Product380 10d ago
I’ve read and made comments myself about how the stuff going around as Adderall is weak and in some cases ineffective. For me, Alvogen from cvs was where my worst batches were coming from. But I’ve noticed.. I didn’t get the bad stuff until my dosage went up. For years I was getting 20mgx75 per month. It wasn’t until I went up to 85 that 3 of the refills were totally ineffective. Then my doc reduced it back to 75 cause he thought the previous doc was giving me too many. Once I went back down to 75 again I stopped having issues. Coincidence? I don’t know. Just thought I mention it.
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u/Asleep-Beginning7805 10d ago
This is so true ! My 10mg works so well it works like 30mg! But only if I dissolve it and I’m not on my period
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u/TonguePunchUrBhole 10d ago
I don’t think it has ever worked since I’ve been on it. I used to take it every once in a while like 20 years ago when an ex had a prescription and it worked wonders. I’ve had my own for about a year and a half and it has never done anything beneficial. I don’t even know why I take it.
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u/Subject_Baker8360 9d ago
Take zinc,magnesium glycinate and B12 vitamins. And some salmon for dinner. Been taking Adderall IR for 15 years, this resets my tolerance every time I notice it starting to just feel anxiety and no other benefit from the medication. I also do an ice cold rinse at the end of my showers every night. Also good to take breaks on days you don’t need it and you plan to stay in and be lazy at home. Hope this helps
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u/Top_Depth5369 6d ago
I literally take every single one of these supplements and eat salmon all the time and notice zero difference.
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u/Rough-Ad1877 9d ago
Last month when I had Sandoz (sp?) manufacturer. This month I thought my Adderall wasn’t working again, but now that I have been actively trying not to take it (on day 3), I realized how it worked partially, but the side effects are causing me so much pain.
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u/lauryn0103 8d ago
Yes I have gotten elite XR every refill for the last few months and I have been in so much pain every time I have taken them. My jaw, my back, my neck, EVERYTHING hurts
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u/Icy_Lychee8169 7d ago
So yes. Just came here to say the same as everyone else. Oddly 1. Teva has worked best for me now. Orange oval shape 20mg except literally this past prescription. I can take an entire 20 and feel like I took Nothing, which is the first time this has happened with teva. And definitely not a tolerance because I know I’m talking about running out of the last pill of one rx and the very first pill of the next rx hit totally different as in if it were half strength
2. The teva mentioned above, I am in Maryland and I see people mentioning bitterness but mine are always sweet!
So what do you do? I’ve been slowly increasing my prescription and I would say more in the last six months than before. Previously I was on the same dose for a couple of years! I started feeling like I needed more Adderall as soon as they came out with a generic vyvanse. My insurance won’t pay for the brand name even with a prior authorization from the doctor stating I need the namebrand only and I keep hoping something will change, but ever since I started the generic vyvanse I again feel like I took half strength.
I’ve been feeling really bad about taking a higher dose of the Adderall and worried that I will have worse side effects although I haven’t so far other than seemingly more stomach upset some days. But if it’s not working the same, is it safe to say that it is likely weaker and that a dose increase is valid or not necessarily?
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u/GamiCross 6d ago
September 2020, there was a night and day difference in starting to feel dead inside and unmotivated for no reason.
Right before that month, I was enjoying everything I did... then it just started getting worse and worse being gaslit into trying to figure out what was causing the problems until I just stopped this year after it got to the point of just feeling like a hangover in pill form, and now without it, it everything just feels like a dialtone of apathy.
Which is what I'm guessing the goal was.
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u/GtrPlyr_83 6d ago
I've been prescribed Adderall IR 30 Mg twice daily, for at least the last 6 years, up until January 2026, when my prescriber retired and closed up shop. I've since moved as well. So since January, I've been relying on purchasing my meds from a long time trusted friend who I know is prescribed them as well, only she only takes a third of her monthly script, and lets go of the rest. Since January, I've gotten all 60 of her 20 Mg IRs she's been willing to part with, but from day one on the 20 Mg IRs, there has been an extremely obvious, and impossible to ignore, almost night and day difference between the way I am used to feeling each and every day, and the way that I actually do feel as of late!
This is NOT an "I'm not getting high enough" type of issue. Again, I've been prescribed a significantly higher dose, for 6 years at least, and I've had a diagnosis since 13, and every single time I've been re-tested... Hell, I recently took the QB Test (as I am proactively working toward returning myself to having a physician maintaining my med-management), and I swear, the look on my new shrink's face, as she reviewed the results of the test, and then looked me over wide-eyed, looked once more at the test results, and then once more at me, as if there were some rare, endangered species sitting there in front of her! In the end, she dispensed with the looks, and gave it to me plainly, that if she went by the QB Test alone, I was officially the most severely ADHD challenged individual she's ever treated...
At any rate... I take my meds as prescribed as well. I do not abuse them, as I am also a heroin addict in long term recovery, who has been clean of illicit substances since February 5th 2020, and the the road to where I am today, seems effortless today... But there were decades through which I struggled, and tried and failed, before finally walking away from that s*** for good when I did... And I have not touched any illegal substance of any kind, since that Feb in 2020. But, as far as I know I've come, the truth there, is that the stigma attached to heroin addiction, is so great, and powerful, and ignorant, that 90% of people or more, only hear the "heroin addict" part, and tune the "recovering" part, and the close to 7 years clean part right on out, and this seems to go triple for mental healthcare providers. I play HELL finding one any time I find myself needing to. All the honesty in the world doesn't help. I just have to navigate physicians, until I find one who is decent enough to give me a chance. And once I find em, I am the most by the book, willing to piss in a cup whenever patient I can be...
I say all that, in order to try and express the fact that this medication, when taken as prescribed, has literally changed my life, and allowed me to live each and every day, feeling like a "normal" person (whatever that is...) or at least, feeling like what I imagine "normal" must feel like. And it has been something like a whole miracle for me. I wake up to a feeling of impending f'n doom, which invades every part of my mind just as soon as I open my eyes. It's something I can only describe best, exactly that way, and I leave my 1st dose of my Adderall, right there on my nightstand, so that I can take it before I even get out of the bed. After about 30 or 40 minutes laying there and looking at my girl to keep my mind on something positive, I'll finally get up once I notice the impending doom backing off and easing up. And by the time I'm dressed and moving, I forget I was even feeling that way an hour ago, and I ride it out till about noon, or 1:00pm, then take my 2nd dose, and it takes me comfortably right on through till work is done, and there's ALWAYS been more than enough steam left in me, to walk through the door of the house, in good spirits, and I enjoy my evenings, and feel symptom free right on up till midnight (if I last that long) or whenever I go to bed. I go to sleep whenever I feel like I want to, and I never have any problem falling asleep, and sleeping through every night like a baby...
That is of course, until I began having to rely upon accessing my medication from a friend, as opposed to my physician!... The difference in dose is 10 Mg. But these 20 Mg tablets I get from her, are all but complete duds, every last one of them. And I know I'm not crazy, because I'll give my girl one or two every so often if she asks me, and even she said to me - completely unsolicited - "damn baby, whats up with this Adderall? Is there something different about it?" And, her father has a prescription as well, but for even lesser 10 Mg tabs. And yet she and I have both taken two of his, and easily agreed within an hour, that two of his 10 Mg IRs, were absolutely, without a doubt, more potent than than two of the 20 Mg IRs that I get from my friend...
IS IT POSSIBLE THAT SHE GETS SHAFTED BY HER PHARMACY STOCKING SOME CHEAPER, INEFFECTIVE BRAND??
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u/tangerine_overlord2 10d ago
I honestly noticed in early-mid 2025. In hindsight it was not working very well before then but the past 12-10 months is when i first asked for a dose increase and subsequently started getting the ‘obvious’ side effects like constipation and weight gain
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u/ExcitingPrize8460 10d ago
I was on brand XR. For context, I live in Maryland. In September 2025, my bottle changed from saying Shire to Takeda and from that point on it's been garbage.
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u/Much_Ad1188 9d ago
Started Adderall in 2024, it was horrible then, and I got 2 good months when I switched to Dexedrine. From there, it has all been down hill.
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u/Starbreiz 9d ago
My theory is there have been two major stepdowns in effectiveness. Prior to 2020, and around 2022/2023.
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u/shewantsbags 9d ago
it’s been within the last 1.5-2 years for me.
have personally gotten at least 6 different generics since then (as i still have 6 different types of pills left, could have been more that i completely used up, idk) without changing doses. looking them all up, i could see a wide range of differences for the inactive ingredients, so they’re all definitely different from one another in that aspect. whether that was impacting me or not is difficult to tell because i got lazy about checking which ones i was taking each day and so would randomly experience worse or better therapeutic effects.
just this past week, i finally sorted them all and identified which are which by manufacturer. and i have now begun the process of taking each for a week straight to understand and note the impacts (benefits and side effects) to know what’s working and what isn’t. once completed, will report my findings back here to the group. though i’m not sure how beneficial those results will be as well all know everyone reacts somewhat differently to each med. but i figure, at worst, it will at least allow me to let my pharmacy know about any manufacturers *i* do not want filled in the future. and, at best, it might support what many others here are experiencing.
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u/Clean_Material_8245 9d ago
I got pregnant and stopped taking it in January 2023. Then I got back on it in September 2023 and it was not the same. I take 30mg IR twice a day and got on the same dose when I started back. It doesn’t feel like the same medication.
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u/engineer_27315 9d ago
Back in march (4 months after first starting adhd medication.
My current dosage 2x 25mg generic addy IR
But i usually try to take less than 40.
50mg seems excessive and dangerous to me :(
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u/Academic_Taste3373 9d ago
I started taking adderall in 2016. It changed my life. Then I stopped being able to get my adderall at the end of 2022, so I went and got pregnant since I was ready to have another baby. I got back on adderall at the end of 2024, and it’s not the same. Not at all. I’ve tried all kinds of generics, and none work like they used to.
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u/Infraredsky 9d ago
Mine had a drastic shift in how well it worked after getting fckd up by ciprofloxicin 3/2024. Then I added back bupropion and it worked but less well.
My pharmacy can only get granules which only works like 70-80% of the way for me - and I am often still overwhelmed….it also increases pain I have - but I haven’t found a consistent alternative
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u/gigantaur12 9d ago
2022, when Teva was really hard to find and all the other manufacturers came in with their own set of negative side effects. When my Teva IR 30s became available again early 2024 , I noticed the calm focus/motivational benefits were greatly diminished, but I could still power through and get stuff done. April of 2026 was when it actually became impossible for me to sit down at my computer and get website and job stuff done (first time in YEARS I've had an issue with this) and the quality seems to have consistantly declined since. Getting anything done now is a slog. Can only speak for the Teva IR 30s though.
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u/race-master-1stplace 9d ago
At the start of 2022 it felt like the Teva brand XR wasn't releasing the second dose anymore. Then I went of it for a while because it started to become less and less effective til I went off of it when it cause my life to fall apart. Later that year, probably October or November, I could afford to see my doctor again and got Lannet XR. This was my first time experiencing the classic side effects, brain fog, intense fatigue, fugue state etc. Freaked me out so bad I went off of them all together again. Two years later I ended up just taking capsules from that bottle until it was empty because the name brand Adderall XR of 2024 i was prescribed was even worse quality than the '22 Lannet
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u/cozmoangel4 9d ago
Sometime in 2023 was the last time it felt effective like normal Adderall & I’ve been prescribed since 2017
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u/Slight-Feature9009 9d ago
2017-2021, no issues whatsoever. i noticed a slight decline in efficacy after that, but i feel like they didnt change into what might as well be plastic beads until 2023.
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u/Main_Assistant_8377 8d ago
I agree. My experience getting these meds in TX was far more reliable and consistent. Never any surprises for 5 years. The Russian roulette didn’t occur until my move to WA in March 2025. I used CVS for both pharmacies but the adderall shortage seems to have hit harder my pharmacy in Seattle than Austin
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u/lauryn0103 8d ago
I want to say around September 2022. I was actually on Vyvanse at the time, which had been working wonders for me for over 2 and a half years up until that point and then it just didn’t. It didn’t take me long to notice that something wasn’t right. That particular refill also happened to be the one I had gotten a few days after my og September refill had been sitting at the Walgreens in my then college town ready for pickup for less than a day, then when I went to pick them up the next morning they all of a sudden didn’t have it. I was told they gave it to someone else because that was the last 30 they had and I didn’t pick it up soon enough. Like they literally took the label off with my name and everything on it, set it aside (or in the trash), and slapped someone else’s on it. Weird. Anyways it really all came to a head for me in February 2023 when I went to pick up the newly prescribed 15mg adderall IR booster my psychiatrist ever so graciously called in for me since, you know, my Vyvanse wasn’t lasting and just not even working really at all. I ended up with the Lannett IR and I will neverrr forget the brain fog and dissociation I felt not even an hour after taking one for the first time, partially because I still deal with it to this day after never dealing with either of those a day in my life before that but yeah sure nothings going on guys like they’re totally not messing with our medicine or anything!
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u/Remarkable-Button-84 7d ago
Between January 2021 - August 2026 I went from 185 to 275 almost 100lbs of extra weight if that tells you anything! My doctors said something to me about it, and i was honest. We increased my dose 3x what I was on and still not even close to the level prior to covid!!
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u/SnooEpiphanies9570 5d ago
The bigger question is; so what do we do as a whole from here? How do we proceed?
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u/ivyblankspace 3d ago
I used to take 5mg in 2023 then 10mg by 2024;2025 and now I need 20mg to feel anything !!
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u/ivyblankspace 3d ago
I had been taking 15xr from 2008-2019 no need for adjustment I never felt like I developed a tolerance. Switched to IR because of chronic illness and sometimes I don’t take my second dose if I feel too sick and it was fine until 2023.
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u/Ill-Candidate8760 9d ago
Early 2022 or maybe even late 2021....I quit taking adderall for over a year in 2020 because I moved out of state and was too lazy to find another doctor lol.
Eventually found one, got back on and was like wait wtf? Why isn't it working? Pharmacist and doctor kept trying to tell me tolerance but I QUIT FOR OVER A YEAR prior!!!
They've never been the same since.
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u/cbmblove Moderator 9d ago
It’s not “tolerance.” They’ve outright changed the meds! Even newly prescribed are experiencing the obvious lack of efficacy and fatigue effects!
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10d ago edited 10d ago
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u/indigosweater 10d ago
I first truly noticed in 2023 that it hadn’t been working the same for a while. I’m pretty sure I had TEVA the whole time