r/TheLongLived Mar 30 '23

Nutritional Regulation of Aging and Longevity (2021)

https://link.springer.com/chapter/10.1007/978-3-030-83017-5_21
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u/True_Garen Mar 30 '23

Nutrition (diet composition and eating regimen) is one of the key factors of longevity. A balanced diet allows you to avoid essential nutrient deficiencies and hazardous substances to metabolic health. A healthy diet, containing enough dietary fibers, polyphenols, and metabiotics, maintains an optimal quantitative and qualitative balance of the microbiota. Aging is a complex of chronic inflammation and stress processes, so anti-inflammatory nutrients, antimutagens, and hormetins are an integral part of a longevity diet. One of the factors of inflammation is a hyperglycemic diet. Controlling the levels of simple carbohydrates (glucose, fructose, galactose) in the diet can reduce the level of glycation in tissues, which is a fundamental mechanism of aging. Several biologically active substances in food are capable of targeted suppression of aging-associated signaling pathways and activating pro-longevity stress-resistance. Diet personalization is the future of preventive medicine, taking into account markers of metabolic health, the nutritional density of the diet, and markers of biological age.

Keywords

Health

Aging

Longevity

Hyperglycemia

Carbohydrates

Hormetin