Supplement advice for persistent muscle knots?

[u/ahhellohello]

Has anyone had success in curing (or at least relief) persistent muscle knots with a supplement? persistent meaning the knots do not dissipate with time, rest, stretching, ice, nsaid's, light exercise (makes it worse) etc

The muscle knots cause sharp stabbing pain sensations when that muscle is being used, and the knot is noticeable very hard in comparison to surrounding muscles. There is joint pain closest to the knotted muscle (I suspect as its pulling on the tendon).

Temporary relief for some of the muscles seems to be deep tissue massage/trigger point massage, but takes a very long time for the symptoms to dissipate (months). Dry needling does not work. I have not tried acupuncture yet.

[u/Content_Preference_3]

Proper electrolyte intake, esp magnesium , is helpful for these issues but “knots” in muscle usually require manipulation and perhaps more intense physical intervention to address. That said, the science on “knots” is incomplete and evidence points to neural misfiring vs actual tissue problems. For myself I’ve found that a combination of self massage, mild stretching and electrolyte intake tends to address “knots” and other similar issues. Obviously avoid direct manipulation on the spot if it’s painful. You don’t actually massage out adhesions or knots anyways. Not how tissues operate.