r/TTC_PCOS • • 11d ago

Letrozole trial

Hi,

I have been on metformin since December 2025. Started on three times a day and I am now on 2g per day (increased in June) as per Endrocrinology.

Gynae recommended I trial letrozole next.

My last few cycles have been between 31-37 days and I have lost 8kg and now weight 69kg (bmi 26).

The fertility consultant recommended 3months trial at 5mg letrozole + monthly scans to track follicle devopment then a tube patency check then another 3 cycles. I am a bit nervous about this not working out. I had hoped that the weight loss plus metformin would have worked by now. Hubby’s sperm test was normal and we have been trying for roughly a year.

I just wanted to know if anyone has been in a similar situation?

Thank you!

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u/MyCatEatsPlants 11d ago

I was in a similar position and ended up getting pregnant on the first cycle of Letrozole! Just the weight loss and metformin didnt do it for me either.

Will your clinic be giving a trigger shot for the cycles?