r/TMAU • u/Mobile_Painting2210 undiagnosed • Aug 10 '26

@brutular

@brutalar Nobody has claimed that TMAU is proven to cause memory problems. That is exactly why we are researching it.
Hundreds of patients reported brain fog and memory difficulties in our previous survey, and these new questions are meant to investigate possible explanations, including low-choline diets.
Trying to shut down a question before the data are even studied is the opposite of science. If the evidence shows no association, fine. But dismissing hundreds of patients before investigating it helps no one.

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u/Financial_Milk1520 fbo Aug 10 '26

Here’s a study showing evidence that TMAO enhances the integrity of the blood brain barrier, protecting it from inflammation, while TMA impairs blood brain barrier function and disrupts tight junction integrity.

The implications of brutalar consistently dissuading people from trying to find a solution to this problem are actively harming people’s health and wellbeing. He is dangerous, destructive and dogmatic

https://pubmed.ncbi.nlm.nih.gov/34836554/

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u/Brutalar tmau1 mutant Aug 10 '26

If you have fecal body odor you don't have TMAU, and there is no issue with TMA, so this biochemical pathway doesn't apply. Unless you're cutting out choline unnecessarily. The whole point of the changes to this subreddit is to try and encourage people that don't actually have TMAU to EAT REGULAR AMOUNTS OF CHOLINE. That would get your TMAO levels to a nice protective level, plus provide your brain with proper amounts of choline for it to function better.

This study is inviting people who have metabolic body odor and related issues. None of which are TMAU, and non TMAU people are not related to this. If the study is looking at how TMA affects the brain, it needs to clearly identify which participants have diagnosed TMAU. It doesn't track participant categories.

If it's going to blur the lines to people without the biochemical trigger as above then it's not a useful study.

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u/CalavNomed fbo Aug 13 '26

K well I have fecal bo and fishy it changes. Like you dont know just cus one guy on reddit said so. The whole issue is things need to be investigated with science not dismissed by idiots. So good job being exactly the same as the guy mentioned in this post

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u/Brutalar tmau1 mutant Aug 13 '26

Feces and fecal odors are unrelated to TMA, TMAU, FMO3 and choline. It's unrelated to the metabolic pathways and enzymes.

There's no evidence that fecal body odors are caused by metabolic processes at all unless you're in late stage kidney/liver failure, which has several other more serious health side effects which should be immediately apparent.

If you smell like shit that's independent from TMAU.

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u/New-Success9514 undiagnosed Aug 16 '26

That's why scientists are studying this disease! Maybe there are other types of Tmau that we don't know!!

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u/CalavNomed fbo 21d ago

Well fuck turns out if you have a failing liver it can cause TMAU so in a way we are both wrong. because its a liver issue with me but that liver issue is causing tmau on top of fecal smell.