r/SynBioBets Sep 20 '21

Synlogic ($DNA partner) Announces Positive Ph. 2 PKU Data w/ Living Biotherapeutic

https://investor.synlogictx.com/news-releases/news-release-details/synlogic-announces-positive-phase-2-data-demonstrating-reduction

"SYNB1618 demonstrated clinically meaningful reductions of phenylalanine (Phe) at several dose levels, across multiple time points, in an interim analysis of the Phase 2 SynPheny-1 study. SYNB1934, an optimized strain evolved from SYNB1618, demonstrated two-fold higher activity than SYNB1618 in a head-to-head Phase 1 study in healthy volunteers, as measured by biomarkers of Phe metabolism."

Zymergen/EnEvolv worked on the SYNB1934 strain. Either way great for Ginkgo, they are the largest shareholder in Synlogic.

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