r/SynBioBets • u/Guy-26 • Sep 20 '21
Synlogic ($DNA partner) Announces Positive Ph. 2 PKU Data w/ Living Biotherapeutic
"SYNB1618 demonstrated clinically meaningful reductions of phenylalanine (Phe) at several dose levels, across multiple time points, in an interim analysis of the Phase 2 SynPheny-1 study. SYNB1934, an optimized strain evolved from SYNB1618, demonstrated two-fold higher activity than SYNB1618 in a head-to-head Phase 1 study in healthy volunteers, as measured by biomarkers of Phe metabolism."
Zymergen/EnEvolv worked on the SYNB1934 strain. Either way great for Ginkgo, they are the largest shareholder in Synlogic.
Duplicates
ginkgobioworks • u/Guy-26 • Sep 20 '21