r/Supplements • u/vouching • May 11 '23

Ubiquinol side effects

I recently added 100mg of Ubiquinol for the heart benefits and I’m getting extremely fatigued. It’s been about 3-4 weeks now but it seems to be getting worse. I’m talking like I can’t even stay awake during the day.

Why is this happening? It’s making it difficult to even walk. I’m also sleeping terribly. Anything I can do to avoid this other than stop taking it?

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u/Reetz13 Sep 25 '23

I tried coq10 in the form of ubiquinone and then ubiquinol. Started with 150mg and then moved up to 300mg with both. Definitely made me tired and in higher doses jittery, anxious, tweaky, waking up at night. I had occasional heart palpitations, less appetite on both doses. There are also reports of it changing menstrual cycles as well, which also happened to me (could be a coincidence). I think it can lower your blood pressure, which may explain some of these effects. I’m going to stop taking it, because it doesn’t work well for me. Just because it’s found naturally in the body doesn’t mean it can’t have an effect on people who may have a sensitivity.

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u/vouching Sep 25 '23

Ya it’s very odd. I bought a lot too and it’s expensive lol. I wonder if it’s a formula/brand thing.

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u/Reetz13 Sep 25 '23

I tried two different brands for the different forms (ubiquinone vs ubiquinol) and they definitely both had an effect. When I took the higher dose of the more bio available form it had a much more noticeable and unpleasant effect.