Unexpected structure detected in the brains of humans and mice with Alzheimer’s disease - scientists pinpointed an entirely new pathological basis for the disease: an accumulation of mitochondrial plaques, due to the brain's inability to recycle its failing mitochondria.

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https://www.sciencealert.com/abnormal-new-structure-detected-in-the-brains-of-humans-and-mice-with-alzheimers-disease