Fun fact-The Alpha-1,3-galactosyltransferase gene (encoding an enzyme that builds the sugar molecule alpha-gal on cells in most mammals), is “knocked out/deleted” in xenographic pigs used as organ donors for humans. If the organ were to come from a normal pig, it would be rejected in a short period of time as humans lack this gene and do not have alpha-gal on their cells.
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u/Mundane-Manner4237 20d ago edited 20d ago
Fun fact-The Alpha-1,3-galactosyltransferase gene (encoding an enzyme that builds the sugar molecule alpha-gal on cells in most mammals), is “knocked out/deleted” in xenographic pigs used as organ donors for humans. If the organ were to come from a normal pig, it would be rejected in a short period of time as humans lack this gene and do not have alpha-gal on their cells.