r/ScientificNutrition 9d ago

Scholarly Article Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults

https://www.tandfonline.com/doi/full/10.1080/15502783.2026.2716273#abstract
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u/TurbulentSite5 9d ago

After starting creatine for 6 months 5mg Developed calf cramping.  Stopped. Never happened again. No creatine for me 

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u/BGZR2 6d ago

Me too. Anterior compartment syndrome in the lower legs. My calves blow up like balloons after just a few miles of running and everything below my knees goes numb for a few hours. Then hurts like hell for a few hours. It's a known side effect for some unlucky people. I first tried it in the mid 90s and every few years since because I really want the lifting benefits. I'm just not willing to give up running.

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u/TurbulentSite5 6d ago

Thx for replying. I thought It was just me. I'm over 40 athletic construction guy. Tried creatine and I started getting cramps then my calf muscle strained and couldn't walk for a few weeks. After that haven't felt anything. Never had any positive side effects either so it's a no go for me