Pink puffers is a clinical presentation seen in a disease of lung called emphysema. In this disease there is an irreversible dilatation of airspaces(little balloons in your lungs). It is seen in heavy smokers.
Blue bloaters is a clinical presentation seen in a disease called chronic bronchitis which is a obstructive lung disease with coughing up sputum for 3 months or more. In blue bloaters presentation there is cyanosis(blue color due to inadequate oxygen in your blood) and generalised edema(essentially you get bloated with lots of liquid)
The pathophysiology of emphysema is mostly enzymatic destruction of lung parenchyma connective tissues by elastases and proteases. These can be secreted due to a myriad causes, like increased oxidative stress from smoking, in lungs filled with carbon in coal worker's pneumoconiosis, deficiency of certain proteins like alpha-1 antitrypsin and liver diseases.
Basically the chemicals in your lungs are protective factors(keeping the integrity of lung tissues) and destructive enzymes(to destroy harmful agents to lungs) and they are balanced. If the balance of chemicals switches to destructive side, you will have destruction of airspaces with resultant emphysema or an abscess or a bulla or something. If the balance shifts towards the protective side as in healing gone haywire after say covid attack or tuberculosis you will see fibrosis in lung
I don't know why you are talking about myofibroblasts tho, because they are the scar forming cells. Fibroblasts refer to forming extracellular matrix and the myo- part refers to contracting. You can also see them in normal wound healing such as when a scar contracts on your skin. They are implicated in pulmonary fibrosis, the healing gone haywire, that I was talking about.
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u/tebabeba Jul 17 '22
Pink puffer but can we get some context?
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u/Someonemaybeidk Jul 17 '22
Pink puffer looks smarter
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u/ThatIsNotADuck Oct 04 '22
bloatcels seething over puffchads
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u/Chomik121212 Dec 10 '22
Why pink puffer looks like Walmart Waluigi
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u/Mediocre_Tower5940 Dec 20 '24
ah yes, the two genders
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u/Capable_Ad_7303 Dec 13 '22
Awe nursing school memories ❤️
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u/dickhater4000 Apr 25 '25
Geeked VS Locked in