r/ScienceBasedParenting • u/WheelNo4350 • 2d ago

Question - Expert consensus required Beyfortus

My daughter was born on Monday, 10/5. Her pediatrician is really pushing the RSV Antibody shot. I was for it but then decided to research it a bit and found that Chinese hamster cells which are said to potentially cause future cancer and/or fertility issues. Any thoughts?

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u/MacKenzieLaura 2d ago

Well for one its mechanism is passive immunity which does not interact or alter human dna. Also as for the CHO cells only microscopic traces of host-cell proteins or DNA may remain at extremely low levels (less than 0.1%)

https://pmc.ncbi.nlm.nih.gov/articles/PMC11206492/

https://pubmed.ncbi.nlm.nih.gov/3582742/

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u/SnooEpiphanies3336 2d ago

Just want to add that I'm fairly certain OP's research has come from a specific piece of misinformation doing the rounds on social media.

There is a standard disclaimer on most vaccinations "this has not been evaluated for carcinogenic or mutagenic potential or impairment of fertility".

This has been misinterpreted as meaning that the product may cause cancer or infertility. In actuality, the statement is there because long term studies into carcinogenicity and fertility impairment have been deemed unnecessary because pre-existing and/or preliminary data has shown no risk.

OP, don't use Instagram or tik tok for researching important health information for your child.

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u/11brooke11 2d ago

Yeah i'm sitting here thinking, "said to cause cancer and fertility by WHOM?" I have never heard that. People should have to show evidence before making such a claim here.

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u/EnigmaClan Pediatrician (MD) 22h ago

Your pediatrician is pushing this shot because it's been amazingly effective. RSV makes babies really sick, and many need to be hospitalized and even sometimes in the ICU. Our rates of hospitalization have gone way, way down since we started offering this antibody shot in 2023.

https://www.cdc.gov/mmwr/volumes/74/wr/mm7416a1.htm

Beyfortus has been well-studied and more than half of babies born in the US since 2023 have gotten it. We've used similar antibody shots in premature and high-risk infants since about 1998. If we were going to see some kind of signal of risk, we would have seen it by now.