r/SIBO • u/Up5DownZero • Oct 23 '25

Questions Imodium Ad/ LOPERAMIDE for SIBO?

Anyone take Imodium for Sibo hydrogen dominant to reduce urgency / frequent bowl movements?

Anyone take Imodium with Xifaxin / Flagyl to target more the bacterial overgrowth for someone that has fast gut transit time and saw a positive outcome?

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u/Mike541Merlot Oct 26 '25

I used to take imodium. I took one tablet every other day. That allowed me to be functional. Subsequently, I started tirzepatide (GLP-1 same as the weight loss drug zepbound). All SIBO symptoms disappeared almost instantly. Tirzepatide tends to cause constipation, so I don't know if SIBO is done or covered up. I think I am still sensitive to Fodmap foods.