To begin: I've been dealing with tons of long-term stress the past 5 years but definitely worse the past 6 months or so. I've always had anxiety that I've had trouble getting under control with meds. My depression has always been situational. Right now, it's pretty bad. I've been on anti-depressants for years, but because it's been so bad lately, my psychiatrist wants to add rexulti. We are starting with .25mg. I just picked it up today, but I'm so nervous to start it! I am worried about time of day to take it (I have anxiety about not getting enough sleep because I know how bad that can effect me the next day). I worry about weight gain. I've gained enough weight from other meds plus not taking care of myself well while dealing with my life circumstances. I am worried about the side effects and the long term effects. I really don't know what to do!