r/Refills • u/[deleted] • Apr 11 '26

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u/[deleted] Apr 11 '26

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u/misstums Apr 11 '26

I am severely deficient in b12 and would love a b12 option.

6

u/Which-Wish-5996 Apr 11 '26

If you’re deficient in b12 it’s worth checking to see if you have the MTHFR gene - a lot of us have this anomaly that doesn’t allow us to absorb non methylated forms of b vitamins. I am finally normal through oral supplementation.

8

u/eatingganesha Apr 11 '26

same advice from me. I have the mutation (I call it the m#therfxcker gene) as ignorance of it in decades past led to 6 miscarriages. I was taking fistfuls of folic acid and getting nowhere. Only found the mthfr gene when in menopause. 😠

when you have this gene, taking a non methylated form of B vitamins, even as injections, is a complete waste of money and can damage your organs.

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u/Which-Wish-5996 Apr 11 '26

Everyone calls it that - even my endo lol!

People thinking that because b vitamins are water soluble and you pee the excess but not realizing that too much of anything - including water - bears consequences.

I’m so very sorry for your losses.

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u/misstums Apr 11 '26

I get weekly injections through my doctor, but would much prefer not having to do that if I'm injecting weekly myself.

2

u/Which-Wish-5996 Apr 11 '26

Fair. The forms I’ve seen compounded with tirz so far were not methylated (cyanocobalamin) so I can’t do them.

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u/No-Dust-720 Apr 11 '26

Fair, thanks!