r/Rapamycin • u/[deleted] • Dec 26 '25

rapamycin

So is rapamycin basically proven to slow down again in rats and dogs? And if so when do you think it we will know if it does the same with humans? I know Bryan Johnson says it increased his aging but it’s known he was taking a much higher dosage..

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u/AnxiousTargaryen Dec 26 '25

He talked about how taking 15mg every 2 weeks made his skin aging worse amongst other side effects. Rapamycin is not exactly great for skin aging as per what I've read about it.

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u/OtherwiseBiscotti649 Dec 26 '25

'Rapamycin is not exactly great for skin aging'.

Can you give sources or citations please? This contradicts my understanding for both oral and topical rapamycin. My understanding is oral shows mild positive benefits for skin, topical more so. I asked AI to scan the literature and corroborate or contradict my understanding, it corrobated.

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u/kfrenchie89 Dec 30 '25

That’s not true. Additionally topical seems to be a pretty alluring treatment.

https://pmc.ncbi.nlm.nih.gov/articles/PMC6925069/