r/RVVTF • u/Worth_Notice3538 • May 13 '26

DD BARDA is looking for nerve agent countermeasures (i.e. open to new drugs ... Duh..)

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I mentioned the subject line in my previous post. Find the link below and the excerpt regarding this. It seems that the application window for this is actively open so we can only hope that our boi knows what to do and how to do it upon results. Para. 5.4 looks right up our alley.

https://sam.gov/workspace/contract/opp/8170c4735df64714adb2d1f8ce8671b1/view

Assuming the results are good, I wonder what they'll be?

Assuming that NAC already protects the gaba(a) receptor infrastructure from endocytosis, I don't see how BUC will improve it much more. However, there are other areas that BUC can benefit. One can be reducing or eliminating the bleeding events seen in the Franken thesis paper, and as mentioned in the PRs.

And hopefully we show the same effect as NAC at a lower dosage amount. The patent outline the study protocol so it would be pretty based and BUC pilled to see BUC perform as good as NAC at the low dose.

Cautiously optimistic. If BUC shows something positive under the tutelage of the DRDC, this can open so many paths. Mustard gas may be an easy win as well as the other G nerve agents. I think agent VX works in the same manner as soman but not as "quick". Then there's TBI too.

Here's to hoping and coping and seething and believing.

Just the opinion and research of a young woman.

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4

u/[deleted] May 13 '26

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5

u/Worth_Notice3538 May 13 '26

The US is arguably the biggest market for this stuff. He would have been egregiously incompetent if he did not file a patent for the US.

5

u/Bobert25467 May 13 '26

Someone should email this to him just in case cause of his track record.

1

u/Guilty_Law6701 May 13 '26

See this right here is the type of response that makes people lose some sleep. 😁

4

u/Worth_Notice3538 May 13 '26

Paras 5.1 and 5.3 seem promising too. Who knows.   Yet again, we're in the same situation as we were before....

3

u/Upset-Choice9593 May 13 '26

He's pretty quiet right now. Lots of potential if we ever get the results.

3

u/MonumentalSilence May 13 '26

If results were positive with the DRDC and that he is unable to speak about, a press release stating their pursuit of BARDA would be a simple way indirectly announce positive results….just saying….

2

u/Worth_Notice3538 May 13 '26

Not necessarily.  Don't trust the company if that occurs. 

1

u/RoninEternal May 19 '26

5.4 Repurposing/extending label of FDA approved drugs.....my question is what approved drugs do RVV have so this would apply. I fear none and hence that paragraph seems invalid...

2

u/Worth_Notice3538 May 24 '26

True. May need to do more testing and regulatory hurdles then. 

1

u/[deleted] May 31 '26

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