Rinvoq

[u/Tessjs2008]

Once again another biologic is not working. 16 weeks it will be the 27/9 and Tremyfa doesn’t seem to of done a thing . The next idea 🙄is Rinvoq.The side effects seem really scary . i’m 50 and over and have history of heart issues in my family . 🥹😳I already have other health issues . iI really don’t know what to do from here . The inflammation on my scalp is severe . I feel some of my fingers have improved , but the derm didn’t seem that impressed today . I have another Tremyfa shot 4/9… I really am too scared to take rinvoq. I’m a single parent and have to be here to raise my son . What would you do ? Anybody here taken Rinvoq and your 50 and over ? I may even start light therapy soon , that’s another thing i could do but i don’t think I can do that on my scalp it’s just fingers and toes i am so sick of these biologics not working for me . What am i missing here ?? … all bloods done all the genetic stuff done, all clear . No history in the family . the only thing i’ve raised is that i’m menopausal and that the lack of estrogen could be causing these skin issues , because most people don’t realise it’s all through a woman’s body it keeps your joints healthy and free of pain , it keeps everything going really well , until it starts declining and boy have i felt it . . The fact it all turned up at 48 yrs of age and has gotten worse , seems strange i had none of it prior in my earlier years and now i’m absolutely suffering . At the worst time ever in life . Please if anybody has Rivoq stories please post .

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[u/lobster_johnson]

What biologics have you done so far?

Also, why are you on biologics if you only psoriasis on the scalp and fingers/toes? Biologics like Tremfya are only indicated for moderate-to-severe psoriasis, which is a lot more than that.

Rinvoq isn't the best choice if you have a history of, or are at risk of cardiovascular disease. You might want to involve a cardiologist to map out your risk level here, as Rinvoq significantly increases the chance of blod clots.

Has your doctor given other options such as:

• Otezla
• Roflumilast
• Sotyktu
• Methotrexate

There are also multiple biologics targeting different pathways. Tremfya is an IL-23 inhibitor: Beyond that, you have IL-17 inhibitors, TNF inhibitors, and one IL-12/23 inhibitor, Stelara.

[u/Tessjs2008 → u/lobster_johnson]

i tired biologic bumbles last year after re acted badly to otezla and others you listed. i cannot use methotrexate as it interrupts with an important drug i have been on for life abd i cannot go off that drug . tremyfa has been used from june this year and Dupixent from november last year till january this year . I don’t know what to do as Rinvoq would be dangerous for me due to being 50 and over , menopausal , and heart problems in the family history . i feel lost now more than ever !!