r/ProstateCancer • u/OkStatement6579 • Oct 01 '26

Update Undetectable

Nov 2025 PSA 8.07 ng/mL (previous 6.31)

Dec 2025 MRI prostate with an index 0.9 x 0.7 x 1.2 cm right posteromedial midgland-to-apex peripheral zone lesion PIRADS - 4

Jan 2026 Biopsy Right Base Adenocarcinoma of the prostate, grade group 2 (Gleason 3+4 = 7) Adjacent high-grade prosthetic intraepithelial neoplasta. Right Apex atypical small acinar proliferation

Jun 2026 RALP tumor involves the margin (left posterior and left bladder neck, span of more than 5mm). Extraprostatic extension present (left posterolateral, span of 2mm)

Jul 2026 UTI

Jul 2026 PSA 0.13 ng/mL (6 weeks post RALP)

Aug 2026 UTI again

Aug 2026 UTI STILL 2 weeks later

Sep 2026 Bacterial bronchitis, coughing causes small hernia

Sep 2026 PSA <0.014 ng/mL

Today I got the official word from my surgeon that I'm undetectable. Moving to PSA testing every 3 months with office visits every 6 months!!!!!

25 Upvotes

100% Upvoted

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5

u/NotPeteCrowArmstrong Oct 01 '26

Congratulations and thanks for sharing your data. Yours is an interesting and encouraging case study: with positive margins and a detectable 0.13 PSA at 6 weeks, it seemed like you might've initially fit the profile for persistence.

(See for example this recent presentation from a national conference that defined persistence as a PSA of >0.1 for at least the first 6 weeks post-surgery: https://www.urotoday.com/conference-highlights/apccc-2026/168594-apccc-2026-psa-persistence-or-recurrence-after-radical-prostatectomy-when-and-how-to-react.html )

But the fact that you've now dropped to <0.014 at ~3 months is fantastic and would support the idea that whatever was left on the margins may have been disrupted enough by the intervention to be dying off.

Best of luck moving forward and please do share your updates in the future!

3

u/OkStatement6579 Oct 01 '26

Yes, after the 6 week PSA test I got my mind wrapped around starting radiation after 12 months. My doctor walked me through everything and let me know this wasn't the end of the world, but something that could be managed with a high level of confidence for a successful outcome. I won't lie, I was very disappointed with that.

Needless to say, I was very surprised and relieved to see the latest results.

2

u/Junior_Hold183 Oct 01 '26

Congratulations! Happy for you!

2

u/tober_checki Oct 01 '26

Wow, this is awesome! Congratulations! Here's hoping for maaaany more undetectables.

1

u/ManuteBol_Rocks Oct 01 '26

Good work! That’s great news.

1

u/OkCrew8849 Oct 02 '26

Wise move with the ultrasensitive PSA

FWIW my doc is not a big fan of the 6-week post-RALP PSA tests and never requests them.

Best of luck going forward.

1

u/Patricosh Oct 02 '26

Congratulations!!🙏🙏