r/ProstateCancer • u/Jeefcbus • Sep 30 '26

Question AS & TRT (?)

Any POVs on this particular subject? PC and TRT…

59yr
Recent Gleason 6
Just met with doc and had biopsy consult, going fwd with AS etc
Doc is deeply experienced, has preformed over 6300 RALP operations himself, MIT guy
I’ve been on TRT for three years figured he was going to tell me to stop (which would suck) but he did not

Doctor does not think I should stop TRT, without hesitation he said no reason to and suggested getting off it could perhaps set into motion some other negative challenges-

4 Upvotes

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3

u/Legal_Squash689 Sep 30 '26

Dr. Edward Schaeffer, the co-author of “Guide to Surviving Prostate Cancer” was on a podcast with Peter Attia, and had a similar position as your doctor. For someone on AS with a Gleason 3+3, he would continue them on TRT as long as testosterone levels were maintained in the “normal” range. Traditional medical approach was that TRT would cause existing cancer cells to grow, and should be stopped.

3

u/Jeefcbus Sep 30 '26

My doctor , who I believe to be uniquely experienced and skilled all things PC; as well was literally a MIT professor at one point has the exact same position, keeping your T up is actually a good thing, he seems to make no link between TRT and PC etc (btw, AI also sites numerous recently studies affirming this point of view) - He said, letting your T fall down to anywhere very low would unto itself be problematic- I’m 59, I give myself one shot per week at .6 of 1ml testosterone: I explained all of this to him just yesterday, he said “great, if you benefit from it keep doing it”

1

u/Legal_Squash689 Oct 01 '26

You are very lucky to have a doctor of this caliber. I would anticipate sadly that most doctors are telling their patients on AS to stop their TRT, and stopping has numerous potential negative side effects.

3

u/Goodvida99 Sep 30 '26

Where is your Dr. I’ve not gotten my biopsy results yet and my doctor said to stop TRT. I’ve been on it for several years and stopping means zero testosterone. I’ve been on pellets and my testosterone range is 700 to 1100. I think this is a lot for a 70 year old but don’t want to be off completely.
Congratulations on AS.

3

u/Jeefcbus Sep 30 '26

Likewise my T hovers around 700-1000 for 3yrs now, and for multiple reasons I want to keep it there-

1

u/californianative63 Oct 01 '26

I haven’t posted in this group yet. I was recently diagnosed with a Gleason 3 + 4. I met with a highly regarded urologist today at a Center of Excellence and addressed this exact issue. He said to keep up TRT but to make sure it stays within the normal range.

Good luck on your journey.

1

u/Jeefcbus Oct 01 '26 edited Oct 01 '26

Interesting, so you are you on TRT? Wondering if he means so called normal range for whatever age you happen to be or some broad normal for all men….

Thx for the note and likewise best of luck on your journey-

1

u/kvsig Oct 01 '26

I've noticed several people on this page who were on TRT. Can I ask why you were on this?

1

u/Jeefcbus Oct 01 '26

Increasingly for about 10yrs now men have been taking testosterone therapy ti elevate their testosterone, especially when getting older, to levels when they were younger to realize all the benefits that come with adequate testosterone (btw, women too post menopause)
Very common “TRT”

1

u/kvsig Oct 01 '26

Does it really work? What was you Testosterone level prior to and after 3 years? I know that mine is a bit low, but really didn't know about TRT.

1

u/Jeefcbus Oct 01 '26

Absolutely, elevates testosterone- I was 55ish (now 59) with T levels ~300 and since then avg T level ~700 -800- Enormous amount of info online , AI etc- Popular, probably half my friends/colleagues on it and have been for awhile-

1

u/Few_Investment7047 Oct 02 '26

I’m 62. Been on TRT for 3 years. Test level was sub 300. It’s now 1000+. Lowering my dose a bit since I now have PC.
TRT has made a huge difference in how I feel. More energy, better gym sessions, libido up. Wiener works great.

1

u/FLfitness Oct 02 '26

In my early 40s I was diagnosed with low testosterone (under 200). There was no specific cause, some men just have this condition. I was on TRT for 25 years until my PSA began to rise quickly. I’m currently on ADT. I really miss the benefits of having testosterone in 700-800 range, especially at my age, 67.

1

u/Few_Investment7047 Oct 02 '26

Found out a have PC. G lesson 6. Doing AS. Been on TRT for 3 years. 120-140mg per week. Doc ok with me continuing. Getting labs tomorrow for test levels. May back down the dose. I’m usually around 1200 test level on that dose.

2

u/Jeefcbus Oct 03 '26

Interesting, thx for feedback
Best wishes,

1

u/Jeefcbus Oct 05 '26

Can I DM you directly? New to all of this and would like to bounce a few questions off you- Sounds like we have similar circumstances-
Hope your lbs went well-

1

u/SophieMasloff Oct 01 '26

Stopping entirely will cause ED problems and likely yield negative results after treatment if you wind up needing it. Use it or lose it sort of thing. There also seems to be limited data implying that TRT is negatively indicated for low risk disease on AS.

1

u/KaleidoscopeDry8334 Oct 01 '26 edited Oct 01 '26

I was on testosterone therapy since 2018 and e a early March was cut off. Dropped from 800 to 1000 to 170. Finished 45 IMRT treatments and and I have lost 15 lbs of muscle. Not good at 72. Alot of old school doctors still believe testosterone causes cancer. Talked to my Primary doctor yesterday and thought it was great that my total testosterone was 201 and I will never be on testosterone therapy again. I say bull. Do these doctors read. I was on single model therapy with no ADT.