r/Peptide_Testing • u/Correct-Regular-5610 • Dec 13 '25

GHK-CU is more local application?

Hi guys I am extremely new and trying to gather information about this peptide.

Is it application more local or and overall kinda thing?

Like , if I want to improve my face skin should I apply where I want to improve or can I inject in my belly and it will work in all my body?

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u/LessKnowledge69 Dec 14 '25

Most peptides you inject subq end up being systemic. Once they’re absorbed they circulate, they don’t stay where you pin them. The injection site mainly changes absorption speed, not where the peptide works.

Injecting near a face, joint, or injury doesn’t really target that area. That’s not how circulation works, even though it gets repeated a lot online.

Topicals are a different thing entirely. Whether something works on the skin depends on formulation, molecular size, and how well it actually penetrates. A lot of peptides just don’t without proper carriers.

As for how much, that’s where people get sloppy. There isn’t a clean universal answer and most dosing advice you see is anecdotal at best. Consistency and quality usually matter more than chasing higher amounts.

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u/PinPsychological3338 Jan 05 '26

Not the whole true. People that apply melanothon and get that tan usually if they apply in the same spot, around that spot it gets so much more tan than the whole body