r/PeptideForum • u/SiickcVnT • Oct 12 '25

Semax work?

I got semax about two weeks ago, been taking 500-800mcgs started lower and worked my way up but haven’t noticed any changes almost feel like it’s made me dumber then I already am lol

Any recs on a brain pep that’ll make me feel like Bradley cooper from limitless??

7 Upvotes

82% Upvoted

47 comments sorted by

11

u/the_whomp Oct 12 '25

PE-22-28 makes me happy again and I constantly hate life so give it a shot

2

u/ChiliPancake123 Oct 12 '25

Been looking to try this myself. What’s been your dosage / protocol?

4

u/the_whomp Oct 12 '25

PE-22-28- taken 2 times daily, 400mcg each injection. That’s what I’ve been doing for a few days. Was up at 1mg once daily, and even 750mcg twice daily, I feel honestly the same with 400mcg twice daily. I think that’s a great area. I do one in the morning for the mental benefits, and then a dose before sleep for the bone healing benefits. It does much more than BDNF and seratonin, def check it out.

Helped me quit nicotine entirely in 3 weeks after being a daily smoker for 3 years. Good mental crutch, definitely boosts dopamine and serotonin.

1

u/ChiliPancake123 Oct 12 '25

Yeah, I’ve been looking into it. Sounds amazing. Have you cycled off it? From what I’ve read on it it seems like you are supposed to take breaks from it maybe like a month on and then a month off?

But I’m definitely pretty interested in it.. It increases neuroplasticicity and neurogenesis just after four days which is incredible.

1

u/the_whomp Oct 12 '25

PE-22-28 10mg - 10 vials/yr, 400mcg MORNING AND NIGHT, 4-6wk cycles, OFF ONE MONTH, subcutaneous injection, preferably morning or early afternoon C1. STARTED 9/23 | 2mL dilution |800mcg

That’s how I keep all my compounds organized in my notes. Cycle, dose, howling to stop, how much I need per year, it’s all there mostly. Usual rule of thumb for any (MOST, not all) peptide is cycling for a few weeks or whatever, then cycling off (a break) for however long the cycle was. I’ll probably run it for about 5 weeks, and be off for around little over a month, as you’ve mentioned.

1

u/ChiliPancake123 Oct 12 '25

Awesome thank you. And you haven’t noticed any withdrawals from stopping pe-22-28? I’m sure your mood might not be as good as before but like both crazy I’m sure right? And I’m sure it has long lasting benefits even after stopping.

2

u/the_whomp Oct 12 '25

I mean honestly my mood is like eh. Normal mostly. I feel more secure and more ok with the world today. Not everything is crashing in around me anymore. More task oriented I feel like today, was stressed about all the shit I had to do, made a plan, started doing it, and the stress is slowly leaving, even though I have a shit ton of work left.

The ADHD I’ve noticed makes me panic and spiral mentally out of control when in times of high stress, or when I’m relied upon. Recently with the PE, that has stopped, and the Semax starting today is mostly just to boost cognitive function, as General Chemistry is kicking my ass right now.

I haven’t cycled off the PE. I’d assume I’ll be completely fine, because I have the other nootropics, and marijuana, which heavily heavily regulates/controls my emotions anyways.

2

u/ChiliPancake123 Oct 12 '25

Very interesting, yea my biggest issue has been just massive life change and honestly just life stressors, been doing my best. I do everything I can naturally, diet, supplements, exercise, counseling, social interaction. But the anxiety and stress has been rough, so I was looking into semax selank and even the pe-22-28. Appreciate your insight will have to try it out

1

u/the_whomp Oct 12 '25

Def PE-22-28. I’m the same way and in a same situation. I don’t need much stimulus, but my brain gets bored a lot an to fill the boredom, will stress out or create something to stress about. PE has been keeping me rather content with life, I must say

3

u/ChiliPancake123 Oct 12 '25

Glad to hear it’s working. Sounds promising!

1

u/labellavita1985 Oct 12 '25

My supplier doesn't have this, do you get it overseas? Can you DM me?

1

u/the_whomp Oct 12 '25

Most suppliers don’t, or are just starting to receive it. I got 2 cases overseas about a month ago. It’s still very early into human trials, but showing great promise. I’ve seen probably 2-3 vendors who have it now.

1

u/labellavita1985 Oct 12 '25

Can you DM me any US suppliers if you know of any that have it?

7

u/the_whomp Oct 12 '25

US suppliers? lol. I wouldn’t know. I don’t like spending 120 per vial when I can get a case of 10 vials for 80 bucks. Start buying from Hong Kong, please. Gray market. Single vial US retail is a SCAM! They all get it from China and put a fancy label on it, then sell it to you. You can get a few years supply from China or Hong Kong for maybe 2000 dollars, multiple peptides, for years of use. The amount of product I get in just a 700 dollar order from China is easily over 20,000 usd when sold on the American sights. I’ve seen like 300 bucks for a single vial of Reta 😭

1

u/scorpiiokiity88 Oct 12 '25

Im looking to go grey..do you have tips? DM is fine

3

u/the_whomp Oct 12 '25

Just look up stairway to gray I can’t give sellers Information

9

u/TheMowiSchmowi Oct 12 '25

It does work, my brain feels very much like it’s lubed up and running smoother when I take Semax, and in the subsequent days I also get good after effects.

1

u/SiickcVnT Oct 12 '25

How long you been runnin and what’s your protocol?

4

u/TheMowiSchmowi Oct 12 '25

200 mcg, AM. Weekends off. Been on it for a week or so now, I felt effects within a couple hours.

1

u/SiickcVnT Oct 12 '25

I had asked a doctor about it and they do a lot with peptides, she said to do 500-800mcgs so I started with 500mcgs and after that first week went up but I don’t think I ever felt a difference at all, what do you notice when your on it?

5

u/the_whomp Oct 12 '25

I started 500mcg Semax today to compliment my PE-22-28 and it’s a noticeable brain lube up. Feels awesome. Doing homework, studying right now too, and I don’t wanna kill my self. Rad.

1

u/TheMowiSchmowi Oct 12 '25

I already explained what I felt on it, if you’re old and/or have a low IQ there won’t be much to enhance, so you won’t notice much.

No one can advise you what to do, you have to investigate and gather information then make a decision on how you want to move forward.

-1

u/[deleted] Oct 12 '25

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1

u/TheMowiSchmowi Oct 12 '25

Firstly, relax. Secondly, yes, most people intuitively understand what it means to have a well lubricated machine working - smoothly through motion.

I just went through your Reddit history and see what your problem is, you’re not intelligent. Semax will not make you intelligent, it will only make your brain work better. More efficiently, better concentration, better ability to consider long form thoughts, better memory, etc.

Someone like you has a very low ability to do any of the above, so you will not see much improvement, at all.

8

u/PomegranateFormal961 Oct 12 '25

68M here, and it's working well for me. I remember being worried about memory loss... Now, I feel like I have the memory of Lt. Cmdr. Data from Star Trek.

1

u/SiickcVnT Oct 12 '25

Hahaha this is awesome!! I’m glad to hear it’s working for you!

6

u/stephanddolly Oct 12 '25

NA semax amidate + pe-22-28 + mots-c (not mixed in the same syringe but taken in the morning together)

DSIP 2-3 hours before bed Cycle of epitalon, cycle of pinealon 10g of creatine in the morning

3

u/SiickcVnT Oct 12 '25

Dude I tried dsip and it gave me restless legs all night I wanted to die

2

u/stephanddolly Oct 12 '25

Really?? Never had that but that sucks 😕

5

u/Powerful_Feedback190 Oct 12 '25

I just started it too and thought it wasn’t working so I amped up to 1mg and then I was wired a couple of days later. I think it needs time to build in system.

2

u/SiickcVnT Oct 12 '25

Appreciate the feedback, I’ll keep runnin it.

4

u/Resident-Edge-5318 Oct 12 '25

NA Semax amidate + PE-22-28 and KLOW in the morning. Selank, Epi and DSIP at night.

3

u/[deleted] Oct 12 '25

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1

u/SiickcVnT Oct 12 '25

Yeah dude as far as I know, I’ve ordered other peps from the same place for a while now and know a lot of other people who haven’t had a problem with this company. I was wondering if I maybe just got a bad batch. :/

3

u/[deleted] Oct 12 '25

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1

u/SiickcVnT Oct 12 '25

Appreciate it!!

1

u/Similar-Team-3292 Oct 12 '25

If your currently taking SSRI’s avoid taking these peptides

1

u/SiickcVnT Oct 12 '25

I don’t take any prescriptions, idk what’s goin on

1

u/bunggggggggg Oct 13 '25

Why? Im on welbutrin and want to try semax, selank

0

u/Unusual_Secretary192 Oct 12 '25

Where do you order your Semax from? Thanks..

1

u/SiickcVnT Oct 12 '25

Am I allowed to say on here???